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Recombinant NGFR 抗体 (AA 281-421)

NGFR 适用: 人 IHC, Diff, StM 宿主: 兔 Monoclonal NGFR-2550R unconjugated Recombinant Antibody
产品编号 ABIN6940198
发货至: 中国
  • 抗原 See all NGFR 抗体
    NGFR (Nerve Growth Factor Receptor (NGFR))
    抗体类型
    Recombinant Antibody
    抗原表位
    • 16
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    AA 281-421
    适用
    • 159
    • 67
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    宿主
    • 92
    • 74
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    克隆类型
    • 90
    • 81
    单克隆
    标记
    • 84
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    This NGFR antibody is un-conjugated
    应用范围
    • 98
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    Immunohistochemistry (IHC), Differentiation (Diff), Staining Methods (StM)
    特异性
    It recognizes a glycoprotein of 75 kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). NGFR is expressed in various neural crest cells and their tumors such as melanocytes, melanomas, neuroblastomas, pheochromocytomas and neurofibromas. Reportedly, anti-NGFR is a reliable marker for desmoplastic and neurotropic melanomas. NGFR is expressed in mature non-neural cells such as perivascular cells, dental pulp cells, lymphoidal follicular dendritic cells, basal epithelium of oral mucosa and hair follicles, prostate basal cells, and myoepithelial cells. Anti-NGFR stains the myoepithelial cells of breast ducts and intra-lobular fibroblasts of breast ducts.
    纯化方法
    Purified by Protein A/G
    免疫原
    Recombinant human p75 NGFR protein fragment (around aa 281-421) (exact sequence is proprietary)
    克隆位点
    NGFR-2550R
    亚型
    IgG
    Top Product
    Discover our top product NGFR Primary Antibody
  • 应用备注

    Positive Control: Neuronal axons, Schwann cells and perineural cells of peripheral nerves or tumors of nerve sheath differentiation e. G. Schwannoma, Neurofibroma. Soma and axons of sensory neurons and ganglionic satellite cells. Melanomas.

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    NGFR (Nerve Growth Factor Receptor (NGFR))
    别名
    NGFR (NGFR 产品)
    别名
    ngfr antibody, wu:fb38c02 antibody, wu:fc10h01 antibody, CD271 antibody, Gp80-LNGFR antibody, TNFRSF16 antibody, p75(NTR) antibody, p75NTR antibody, LNGFR antibody, RNNGFRR antibody, Tnfrsf16 antibody, p75 antibody, NRH1b antibody, fullback antibody, nrh1 antibody, p75ntr antibody, tnfrsf16 antibody, p75NGFR antibody, nerve growth factor receptor antibody, neurotrophin receptor associated death domain antibody, nerve growth factor receptor S homeolog antibody, nerve growth factor receptor (TNFR superfamily, member 16) antibody, NGFR antibody, nradd antibody, Ngfr antibody, ngfr.S antibody
    分子量
    75kDa
    基因ID
    4804
    UniProt
    P08138
    途径
    NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
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