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MME 抗体 (AA 297-483)

Name: MME 抗体 (AA 297-483)
Brand: antibodies-online
SKU: ABIN6940058
Availability: OutOfStock

MME 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal MME-1870 unconjugated

Western Blot Analysis of kidney tissue lysate using CD10 Mouse Monoclonal Antibody (MME/1870). (MME 抗体 (AA 297-483))

Analysis of Protein Array containing more than 19,000 full-length human proteins using CD10 Mouse Monoclonal Antibody (MME/1870) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. (MME 抗体 (AA 297-483))

PAr

Formalin-fixed, paraffin-embedded human Colon stained with CD10 Mouse Monoclonal Antibody (MME/1870). (MME 抗体 (AA 297-483))

IHC

Formalin-fixed, paraffin-embedded human Kidney stained with CD10 Mouse Monoclonal Antibody (MME/1870). (MME 抗体 (AA 297-483))

7 images

产品编号 ABIN6940058

发货至: 中国

Datasheet as PDF

抗原 See all MME 抗体

MME (Membrane Metallo-Endopeptidase (MME))
抗原表位
14

8

8

8

7

7

7

7

6

5

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 297-483
适用
190

44

37

3

2

2

2

2

2

1

1

1

1
人
宿主
99

96

2
小鼠
Compatible Secondaries
克隆类型
105

91

2
单克隆
标记
105

20

16

12

9

5

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This MME antibody is un-conjugated
应用范围
109

78

76

66

34

27

19

18

10

8

5

4

3

3

2

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), Staining Methods (StM)

特异性

Recognizes a 100 kDa glycoprotein, identified as CD10, also known as Common Acute Lymphocytic Leukemia Antigen (CALLA). It is a cell surface enzyme with neutral metalloendopeptidase activity, which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt's, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML). It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue. CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells.

纯化方法

Purified by Protein A/G

免疫原

Recombinant human CD10 protein fragment (aa297-483) (exact sequence is proprietary)

克隆位点

MME-1870

亚型

IgG2c kappa

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应用备注

Positive Control: Kidney, Prostate or Small Intestine.
Known Application: Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

限制

仅限研究用
浓度

200 μg/mL

缓冲液

10 mM PBS with 0.05 % BSA & 0.05 % azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-80 °C

储存方法

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

有效期

24 months
抗原

MME (Membrane Metallo-Endopeptidase (MME))

别名

MME (MME 产品)

别名

CALLA antibody, CD10 antibody, NEP antibody, SFE antibody, 6030454K05Rik antibody, C85356 antibody, Nep antibody, neprilysin antibody, membrane metalloendopeptidase antibody, membrane metallo endopeptidase antibody, membrane metallo-endopeptidase antibody, MME antibody, Mme antibody

物质类

Chemical

分子量

100kDa

基因ID

4311

UniProt

P08473

途径

RTK signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration