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Ki-67 抗体 (AA 2293-2478)

MKI67 适用: 人 IHC, WB, FACS, IF, StM 宿主: 小鼠 Monoclonal MKI67-2462 unconjugated
产品编号 ABIN6940053
发货至: 中国
  • 抗原 See all Ki-67 (MKI67) 抗体
    Ki-67 (MKI67) (Antigen Identified By Monoclonal Antibody Ki-67 (MKI67))
    抗原表位
    • 16
    • 16
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    • 7
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    AA 2293-2478
    适用
    • 180
    • 67
    • 41
    • 5
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    宿主
    • 145
    • 38
    • 4
    • 3
    小鼠
    克隆类型
    • 136
    • 52
    单克隆
    标记
    • 83
    • 13
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    • 5
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    This Ki-67 antibody is un-conjugated
    应用范围
    • 84
    • 73
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    • 14
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    Immunohistochemistry (IHC), Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Staining Methods (StM)
    特异性
    Ki-67 antigen is a nuclear, non-histone protein that is present in all stages of the cell cycle except G0. This characteristic makes Ki-67 an excellent marker for proliferating cells and is commonly used as one of the prognostic factors in cancer studies. A correlation has been demonstrated between Ki-67 index and the histo-pathological grade of neoplasms. Assessment of Ki-67 expression in renal and ureter tumors shows a correlation between tumor proliferation and disease progression, thus making it possible to differentiate high-risk patients. Ki-67 expression may also prove to be important for distinguishing between malignant and benign peripheral nerve sheath tumors. Ki-67 labeling index has been shown to be a prognostic marker in a number of neoplasms including grade II astrocytoma, oligodendroglioma, colon carcinoma, and breast carcinoma. In general, Ki-67 is a good marker of proliferating cell populations.
    纯化方法
    Purified by Protein A/G
    免疫原
    Recombinant human Ki67 protein fragment (around aa 2293-2478) (exact sequence is proprietary)
    克隆位点
    MKI67-2462
    亚型
    IgG2b kappa
    Top Product
    Discover our top product MKI67 Primary Antibody
  • 应用备注

    Positive Control: Any actively proliferating cells. Skin, Tonsil or Lymph Node.

    Known Application: Western Blot (1-2 μg/mL), Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    Ki-67 (MKI67) (Antigen Identified By Monoclonal Antibody Ki-67 (MKI67))
    别名
    MKI67 (MKI67 产品)
    别名
    MKI67 antibody, kia antibody, mki67 antibody, MGC132156 antibody, D630048A14Rik antibody, Ki-67 antibody, Ki67 antibody, KIA antibody, MIB-1 antibody, marker of proliferation Ki-67 antibody, marker of proliferation Ki-67 L homeolog antibody, marker of proliferation Ki-67 S homeolog antibody, antigen identified by monoclonal antibody Ki 67 antibody, antigen identified by monoclonal antibody Ki-67 antibody, nucleolar protein interacting with the FHA domain of MKI67 antibody, MKI67 antibody, mki67 antibody, mki67.L antibody, mki67.S antibody, Mki67 antibody, NIFK antibody
    分子量
    345kDa and 395kDa
    基因ID
    4288
    UniProt
    P46013
    途径
    Glycosaminoglycan Metabolic Process
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