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MCM7 抗体 (AA 195-319)

This anti-MCM7 antibody is a 小鼠 单克隆 antibody detecting MCM7 in WB, IHC 和 StM. Suitable for 人.
产品编号 ABIN6940018
发货至: 中国

Quick Overview for MCM7 抗体 (AA 195-319) (ABIN6940018)

抗原

See all MCM7 抗体
MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This MCM7 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Staining Methods (StM)

克隆位点

MCM7-1466
  • 抗原表位

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    AA 195-319

    纯化方法

    Purified by Protein A/G

    免疫原

    Recombinant human MCM7 protein fragment (aa195-319)

    亚型

    IgG2b kappa
  • 应用备注

    Positive Control: MCF-7, HEK-293, A549, Raji or Ramos cells. Tonsil.

    Known Application: Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))

    别名

    MCM7

    背景

    MCM7 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that is essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumor suppressor protein RB1/RB.

    分子量

    88kDa

    基因ID

    4176

    UniProt

    P33993

    途径

    DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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