LHCGR 抗体 (AA 70-410)
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- 抗原 See all LHCGR 抗体
- LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))
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抗原表位
- AA 70-410
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This LHCGR antibody is un-conjugated
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应用范围
- Immunofluorescence (IF), Flow Cytometry (FACS)
- 特异性
- Recognizes a protein of 78-85 kDa, which is identified as Luteinizing hormone / choriogonadotropin receptor. Luteinizing hormone plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Choriogonadotropin production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone / choriogonadotropin receptor (LHCGR) as a seven transmembrane, G protein-coupled receptor glycoprotein. LHCGR influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of LHCGR on breast carcinoma correlates in part to the degree of tumor differentiation. LHCGR -positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women.
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Recombinant fragment (around aa 70-410) of human LHCGR protein (exact sequence is proprietary)
- 克隆位点
- LHCGR-1415
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product LHCGR Primary Antibody
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- 应用备注
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Positive Control: HepG2 or Jurkat cells. Ovary or Testis.
Known Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))
- 别名
- LHCGR (LHCGR 产品)
- 别名
- HHG antibody, LCGR antibody, LGR2 antibody, LH/CG-R antibody, LH/CGR antibody, LHR antibody, LHRHR antibody, LSH-R antibody, ULG5 antibody, Gpcr19-rs1 antibody, LH-R antibody, Lhr antibody, LSHR antibody, lhr antibody, GTHR-II antibody, zfGTHR-II antibody, LHCGR antibody, LOC100222883 antibody, lh-r antibody, LOC100305044 antibody, luteinizing hormone/choriogonadotropin receptor antibody, luteinizing hormone/choriogonadotropin receptor L homeolog antibody, luteinizing hormone receptor antibody, LHCGR antibody, Lhcgr antibody, lhcgr antibody, lhcgr.L antibody, lhr antibody, LOC100305044 antibody
- 分子量
- 78-85kDa
- 基因ID
- 3973
- UniProt
- P22888
- 途径
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, cAMP Metabolic Process, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
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