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FAS 抗体 (AA 26-96)

Name: FAS 抗体 (AA 26-96)
Brand: antibodies-online
SKU: ABIN6939781
Availability: OutOfStock

FAS 适用: 人 FACS, IHC, ELISA, IF, Coat, StM 宿主: 小鼠 Monoclonal FAS-3112 unconjugated

Formalin-fixed, paraffin-embedded human colon stained with CD95 Mouse Monoclonal Antibody (FAS/3112). (FAS 抗体 (AA 26-96))

IHC

SDS-PAGE Analysis Purified CD95 Mouse Monoclonal Antibody (FAS/3112). (FAS 抗体 (AA 26-96))

SDS

Analysis of Protein Array containing more than 19,000 full-length human proteins using CD95 Mouse Monoclonal Antibody (FAS/3112). (FAS 抗体 (AA 26-96))

PAr

IHC

4 images

产品编号 ABIN6939781

发货至: 中国

Datasheet as PDF

抗原 See all FAS 抗体

FAS (TNF Receptor Superfamily, Member 6 (FAS))
抗原表位
24

16

16

9

8

6

5

5

4

4

4

4

3

3

3

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 26-96
适用
208

62

59

19

5

4

2

2

1

1
人
宿主
156

86

4

2

1

1

1
小鼠
Compatible Secondaries
克隆类型
156

93

1
单克隆
标记
111

26

25

13

11

7

3

3

3

3

3

3

3

3

3

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
This FAS antibody is un-conjugated
应用范围
156

112

70

55

34

34

26

26

25

19

16

9

8

5

5

4

4

2

2

2

1

1
Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Coating (Coat), Staining Methods (StM)

特异性

This MAb specifically recognizes CD95, also known as Fas, a transmembrane glycoprotein with a MW of 40-45 kDa, containing 8 kDa of N-glycoside-linked polysaccharide. It is a receptor for TNFSF6/FASLG, a member of the nerve growth factor receptor/tumor necrosis factor superfamily, mediating receptor-triggered apoptosis. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation, which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). CD95 antigen is expressed on the surface of various cell types, preferentially on the CD45RAlow CD45ROhigh subset of memory T lymphocytes.

纯化方法

Purified by Protein A/G

免疫原

Recombinant fragment (around aa26-96) of human CD95 (FAS) protein (exact sequence is proprietary)

克隆位点

FAS-3112

亚型

IgG2b kappa

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anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 87-109), (N-Term) antibody
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FAS 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

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FAS 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 2G3 unconjugated

anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 20-119) antibody
FAS 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 5B4 unconjugated

anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 1-335) antibody
FAS 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1B6 unconjugated

anti-TNF Receptor Superfamily, Member 6 (FAS) (AA 185-211) antibody
FAS 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated

应用备注

Positive Control: MCF-7 cells (IF/FACS). Human hepatocellular or bladder carcinoma (IHC).
Known Application: ELISA (For coating, order Ab without BSA), Immunohistochemistry (Formalin-fixed) (0.5-1.0 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

限制

仅限研究用
浓度

200 μg/mL

缓冲液

10 mM PBS with 0.05 % BSA & 0.05 % azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-80 °C

储存方法

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

有效期

24 months
抗原

FAS (TNF Receptor Superfamily, Member 6 (FAS))

别名

FAS (FAS 产品)

别名

ALPS1A antibody, APO-1 antibody, APT1 antibody, CD95 antibody, FAS1 antibody, FASTM antibody, TNFRSF6 antibody, AI196731 antibody, APO1 antibody, TNFR6 antibody, Tnfrsf6 antibody, lpr antibody, Fas cell surface death receptor antibody, Fas (TNF receptor superfamily member 6) antibody, FAS antibody, Fas antibody, fas antibody

分子量

38-50kDa

基因ID

355

UniProt

P25445

途径

p53 Pathway, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity