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IGKC 抗体

IGKC 适用: 人 IHC, StM, WB, FACS 宿主: 小鼠 Monoclonal KLC264 unconjugated
产品编号 ABIN6939745
发货至: 中国
  • 抗原 See all IGKC products
    IGKC (Immunoglobulin kappa Constant (IGKC))
    适用
    宿主
    • 9
    • 9
    小鼠
    克隆类型
    • 11
    • 7
    单克隆
    标记
    • 13
    • 2
    • 1
    • 1
    • 1
    This IGKC antibody is un-conjugated
    应用范围
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), Staining Methods (StM), Western Blotting (WB), Flow Cytometry (FACS)
    特异性
    This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
    纯化方法
    Purified by Protein A/G
    免疫原
    Recombinant human Ig kappa chain
    克隆位点
    KLC264
    亚型
    IgG1 kappa
  • 应用备注

    Positive Control: 293T, Raji or hPBL cells. Tonsil or Spleen.

    Known Application: Western Blot (1-2 μg/mL), Flow Cytometry (1-2 μg/million cells), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    IGKC (Immunoglobulin kappa Constant (IGKC))
    别名
    IGKC (IGKC 产品)
    别名
    HCAK1 antibody, IGKCD antibody, Km antibody, IGKC antibody, Igk-C antibody, immunoglobulin kappa constant antibody, immunoglobulin kappa constant L homeolog antibody, IGKC antibody, LOC708048 antibody, igkc antibody, igkc.L antibody, Igkc antibody
    分子量
    ~22.5kDa
    基因ID
    3514
    UniProt
    P01601, P01834
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