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Recombinant IGHM 抗体

IGHM 适用: 人 IHC, StM, FACS, IF, ELISA, Coat 宿主: 小鼠 Monoclonal rIGHM-1623 unconjugated Recombinant Antibody
产品编号 ABIN6939724
发货至: 中国
  • 抗原 See all IGHM products
    IGHM (Immunoglobulin Heavy Constant mu (IGHM))
    抗体类型
    Recombinant Antibody
    适用
    • 25
    • 1
    • 1
    宿主
    • 13
    • 12
    小鼠
    克隆类型
    • 16
    • 9
    单克隆
    标记
    • 21
    • 1
    • 1
    • 1
    • 1
    This IGHM antibody is un-conjugated
    应用范围
    • 12
    • 12
    • 10
    • 7
    • 6
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
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    Immunohistochemistry (IHC), Staining Methods (StM), Flow Cytometry (FACS), Immunofluorescence (IF), ELISA, Coating (Coat)
    特异性
    Recognizes a protein of 75 kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. IgM antibody is prominent in early immune responses to most antigens. Aberrant levels are associated with immune deficiency states, hereditary deficiencies, myeloma, Waldenstrom's macroglobulinemia, chronic infection and hepatocellular disease. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin s lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
    纯化方法
    Purified by Protein A/G
    免疫原
    Recombinant human full-length IGHM protein
    克隆位点
    RIGHM-1623
    亚型
    IgG1 kappa
  • 应用备注

    Positive Control: 293T, Raji or hPBL cells. Human tonsil or spleen (IHC).

    Known Application: ELISA (For coating, order antibody without BSA), ,Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    IGHM (Immunoglobulin Heavy Constant mu (IGHM))
    别名
    IGHM (IGHM 产品)
    别名
    AI326478 antibody, Igh-6 antibody, Igh-M antibody, Igh6 antibody, Igm antibody, muH antibody, ighm1 antibody, wu:fj14a08 antibody, zgc:101769 antibody, AGM1 antibody, MU antibody, VH antibody, immunoglobulin heavy constant mu antibody, Ighm antibody, ighm antibody, IGHM antibody
    分子量
    50-75kDa
    基因ID
    3507
    UniProt
    P01871, P20769
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