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HLA-DRA 抗体

HLA-DRA 适用: 人 IHC, FACS, IF, StM 宿主: 小鼠 Monoclonal 19-26-1-same as MB-26-1 unconjugated
产品编号 ABIN6939638
发货至: 中国
  • 抗原 See all HLA-DRA 抗体
    HLA-DRA (HLA Class II DR alpha (HLA-DRA))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This HLA-DRA antibody is un-conjugated
    应用范围
    • 45
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    Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Staining Methods (StM)
    特异性
    This MAb reacts with the HLA-DR antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kDa alpha (heavy) chain and a 28 kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 Molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense cytoplasmic staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts.
    纯化方法
    Purified by Protein A/G
    免疫原
    Raji cells
    克隆位点
    19-26-1-same as MB-26-1
    亚型
    IgG2a kappa
    Top Product
    Discover our top product HLA-DRA Primary Antibody
  • 应用备注

    Positive Control: Raji, Ramos, Daudi or HuT78 cells. Tonsil or lymph node.

    Known Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    HLA-DRA (HLA Class II DR alpha (HLA-DRA))
    别名
    HLA-DRA (HLA-DRA 产品)
    别名
    HLA-DRA1 antibody, MLRW antibody, DR-alpha antibody, HLA-DRA antibody, Mamu-DRA1 antibody, major histocompatibility complex, class II, DR alpha L homeolog antibody, major histocompatibility complex, class II, DR alpha antibody, hla-dra.L antibody, HLA-DRA antibody, MAMU-DRA antibody, BOLA-DRA antibody
    分子量
    36kDa (α, chain) and 27kDa (β, chain)
    基因ID
    3122
    UniProt
    P01903
    途径
    TCR Signaling, CXCR4-mediated Signaling Events, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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