Recombinant HLA DQ 抗体
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- 抗原 See all HLA DQ (HLA-DQ) products
- HLA DQ (HLA-DQ) (MHC Class II HLA-DQ (HLA-DQ))
- 抗体类型
- Recombinant Antibody
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适用
- 人, Pig
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This HLA DQ antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- Recognizes a DQ antigen, which is a dimer of 60 kDa. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons, exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation.This MAb strongly blocks cytotoxicity activity of T4-positive cytotoxic T cell clones.
- 纯化方法
- Purified by Protein A/G
- 免疫原
- T4-positive CTL clone HG-38
- 克隆位点
- RSPV-L3
- 亚型
- IgG1 kappa
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anti-MHC Class II HLA-DQ (HLA-DQ) antibody
HLA-DQ 适用: 人, Pig FACS, IF, IHC (fro) 宿主: 兔 Monoclonal HLA-DQA1-2866R unconjugated Recombinant Antibody
anti-MHC Class II HLA-DQ (HLA-DQ) antibodyHLA-DQ 适用: 人, Pig FACS, IF 宿主: 小鼠 Monoclonal SPV-L3 unconjugated
anti-MHC Class II HLA-DQ (HLA-DQ) antibodyHLA-DQ 适用: 人, Pig FACS, IF, ELISA, Coat 宿主: 小鼠 Monoclonal SPM422 unconjugated
anti-MHC Class II HLA-DQ (HLA-DQ) antibodyHLA-DQ 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal B-K27 unconjugated
anti-MHC Class II HLA-DQ (HLA-DQ) antibodyHLA-DQ 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal B-K27 unconjugated
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- 应用备注
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Positive Control: Raji cells. Tonsil or lymph node.
Known Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Frozen only) (0.5-1 μg/mL for 30 minutes at RT)Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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