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PD-L1 抗体 (AA 39-191)

PD-L1 适用: 人, 小鼠 WB, FACS, IHC, ELISA, IF, Coat, StM 宿主: 小鼠 Monoclonal PDL1-2746 unconjugated
产品编号 ABIN6939571
发货至: 中国
  • 抗原 See all PD-L1 抗体
    PD-L1 (CD274 (PD-L1))
    抗原表位
    • 29
    • 16
    • 15
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    AA 39-191
    适用
    • 165
    • 113
    • 62
    • 6
    • 5
    • 5
    • 5
    • 1
    • 1
    人, 小鼠
    宿主
    • 131
    • 53
    • 19
    • 4
    • 2
    • 1
    小鼠
    克隆类型
    • 113
    • 95
    • 2
    单克隆
    标记
    • 91
    • 15
    • 14
    • 11
    • 8
    • 5
    • 4
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    • 4
    • 4
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    This PD-L1 antibody is un-conjugated
    应用范围
    • 132
    • 102
    • 55
    • 40
    • 35
    • 28
    • 17
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    • 10
    • 6
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    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Coating (Coat), Staining Methods (StM)
    纯化方法
    Purified by Protein A/G
    免疫原
    Recombinant fragment (around aa 39-191) of human CD274 (PD-L1) protein (exact sequence is proprietary)
    克隆位点
    PDL1-2746
    亚型
    IgG2b kappa
    Top Product
    Discover our top product PD-L1 Primary Antibody
  • 应用备注

    Positive Control: Heart, Placenta, Spleen or Tonsil tissue. RAW, HEK293 or HepG2 cell lysates. Jurkat cells.

    Known Application: ELISA (For coating, order antibody without BSA), Western Blot (1-2 μg/mL),Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    PD-L1 (CD274 (PD-L1))
    别名
    CD274 (PD-L1 产品)
    别名
    B7-H antibody, B7H1 antibody, PD-L1 antibody, PDCD1L1 antibody, PDCD1LG1 antibody, PDL1 antibody, A530045L16Rik antibody, B7h1 antibody, Pdcd1l1 antibody, Pdcd1lg1 antibody, Pdl1 antibody, RGD1566211 antibody, CD274 molecule antibody, CD274 antigen antibody, programmed cell death 1 ligand 2 antibody, CD274 antibody, Cd274 antibody, PDCD1LG2 antibody
    背景
    PD-L1 is a checkpoint regulator in immune cells, it is expressed on immune or non-hematopoietic cells. Expression of the protein is seen during pregnancy where it has a role in suppressing the immune system. PD-L1 induces an inhibitory signal in activated T-cells and promotes T-cell apoptosis. It is overexpressed in a number of different cancers where it is believed to play a significant role in the cancer s ability to evade the immune system.
    分子量
    37-50kDa
    基因ID
    29126
    UniProt
    Q9NZQ7
    途径
    Cancer Immune Checkpoints
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