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GP2 抗体 (AA 35-179)

GP2 适用: 人 IHC, ELISA, Coat, StM 宿主: 小鼠 Monoclonal GP2-1712 unconjugated
产品编号 ABIN6939542
发货至: 中国
  • 抗原 See all GP2 products
    GP2 (Glycoprotein 2 (Zymogen Granule Membrane) (GP2))
    抗原表位
    • 27
    • 8
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 35-179
    适用
    • 47
    • 8
    • 4
    • 2
    • 2
    • 1
    宿主
    • 32
    • 24
    小鼠
    克隆类型
    • 28
    • 28
    单克隆
    标记
    • 28
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This GP2 antibody is un-conjugated
    应用范围
    • 33
    • 31
    • 23
    • 19
    • 19
    • 12
    • 9
    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC), ELISA, Coating (Coat), Staining Methods (StM)
    无交叉反应
    小鼠
    纯化方法
    Purified by Protein A/G
    免疫原
    Recombinant fragment of human GP2 protein (around aa 35-179) (exact sequence is proprietary)
    克隆位点
    GP2-1712
    亚型
    IgG2b kappa
  • 应用备注

    Positive Control: PANC-1 cells. Pancreas.

    Known Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    GP2 (Glycoprotein 2 (Zymogen Granule Membrane) (GP2))
    别名
    GP2 (GP2 产品)
    别名
    ZAP75 antibody, 2310037I18Rik antibody, AV060639 antibody, gp80 antibody, glycoprotein 2 antibody, glycoprotein 2 (zymogen granule membrane) antibody, GP2 antibody, Gp2 antibody
    物质类
    Viral Protein
    背景
    GP2 (glycoprotein 2), also known as ZAP75, is a 537 amino acid secreted protein. It is an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. GP2 is cleaved and then released into the pancreatic duct along with exocrine secretions. GP2 binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). GP2 is also expressed on the apical plasma membrane of specialized microfold (M) cells among enterocytes and serves as a transcytotic receptor for mucosal antigens. M cells are considered a promising target for oral vaccination against various infectious diseases.
    分子量
    59kDa
    基因ID
    2813
    UniProt
    P55259
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