AMPD3 抗体
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- 抗原 See all AMPD3 抗体
- AMPD3 (Adenosine Monophosphate Deaminase 3 (AMPD3))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This AMPD3 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Staining Methods (StM)
- 特异性
- It recognizes a protein of ~90 kDa, which is identified as Adenosine Monophosphate Deaminase, isoform E (AMPD3). It has 767 amino acids and is assigned an EC 3.5.4.6. It is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. AMPD3 gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. This MAb shows reactivity with cells of the erythroid lineage at all stages of maturation in the peripheral blood, bone marrow, and fetal liver. Non-erythroid lineages are negative by flow cytometry. This MAb is useful in the diagnosis of erythroleukemia, identification of bone marrow erythroid precursors, gating erythroid nucleated precursor cells from malignant cells in bone marrow specimens.
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Recombinant full-length human AMDP3 protein
- 克隆位点
- AMPD3-901
- 亚型
- IgG2b kappa
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- 应用备注
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Positive Control: RBC. Fetal liver, Spleen or Placenta.
Known Application: Immunohistochemistry (Formalin-fixed) (2-4 μg/mL for 30 minutes at RT) (Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- AMPD3 (Adenosine Monophosphate Deaminase 3 (AMPD3))
- 别名
- AMPD3 (AMPD3 产品)
- 别名
- ampd3 antibody, fi25h10 antibody, wu:fi25h10 antibody, zgc:55390 antibody, MGC108215 antibody, adenosine monophosphate deaminase 3 antibody, adenosine monophosphate deaminase 3b antibody, AMP deaminase 3 antibody, AMPD3 antibody, ampd3b antibody, PTRG_08116 antibody, ampd3 antibody, Ampd3 antibody
- 分子量
- ~90kDa
- 基因ID
- 272
- UniProt
- Q01432
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