Growth Hormone 1 抗体 (AA 58-187)
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- 抗原 See all Growth Hormone 1 (GH1) 抗体
- Growth Hormone 1 (GH1)
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抗原表位
- AA 58-187
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Growth Hormone 1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Staining Methods (StM)
- 纯化方法
- Purified by Protein A/G
- 免疫原
- A recombinant fragment (around aa58-187) of human Growth Hormone (GH) protein (exact sequence is proprietary)
- 克隆位点
- SPM106
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product GH1 Primary Antibody
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- 应用备注
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Positive Control: Pituitary cells. Human pituitary tissue (IHC).
Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- Growth Hormone 1 (GH1)
- 别名
- GH1 (GH1 产品)
- 背景
- Pituitary growth hormone (GH) plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Anti-GH is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly).
- 分子量
- 20kDa
- 基因ID
- 2688
- UniProt
- P01241
- 途径
- NF-kappaB Signaling, JAK/STAT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Response to Growth Hormone Stimulus, Regulation of Hormone Biosynthetic Process
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