NKX2-8 抗体 (AA 10-123)
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- 抗原 See all NKX2-8 抗体
- NKX2-8 (NK2 Homeobox 8 (NKX2-8))
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抗原表位
- AA 10-123
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This NKX2-8 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Human recombinant NKX2.8 protein fragment (around aa 10-123) (exact sequence is proprietary)
- 克隆位点
- NKX28-2547
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product NKX2-8 Primary Antibody
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- 应用备注
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Positive Control: Human Liver, Kidney or Thyroid tissue (IHC).
Known Application: Western Blot (0.5 μg-1 μg/mL), Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- NKX2-8 (NK2 Homeobox 8 (NKX2-8))
- 别名
- NKX2-8 (NKX2-8 产品)
- 别名
- NKX2.8 antibody, NKX2H antibody, Nkx2-9 antibody, Nkx-2.9 antibody, Nkx2-8 antibody, Nkx2.9 antibody, tinman antibody, NK2 homeobox 8 antibody, NK2 homeobox 9 antibody, NKX2-8 antibody, Nkx2-9 antibody, Nkx2-8 antibody
- 背景
- The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects.
- 分子量
- 26kDa
- 基因ID
- 26257
- UniProt
- O15522
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