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Frataxin 抗体 (AA 57-210)

FXN 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal FXN-2124 unconjugated
产品编号 ABIN6939442
发货至: 中国
  • 抗原 See all Frataxin (FXN) 抗体
    Frataxin (FXN)
    抗原表位
    • 14
    • 8
    • 7
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 57-210
    适用
    • 66
    • 22
    • 13
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 58
    • 15
    小鼠
    克隆类型
    • 60
    • 13
    单克隆
    标记
    • 42
    • 6
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Frataxin antibody is un-conjugated
    应用范围
    • 56
    • 39
    • 21
    • 12
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Staining Methods (StM)
    纯化方法
    Purified by Protein A/G
    免疫原
    Recombinant fragment of human Frataxin (FXN) protein (around aa 57-210) (exact sequence is proprietary)
    克隆位点
    FXN-2124
    亚型
    IgG2b kappa
  • 应用备注

    Positive Control: HepG2, Panc-2, HL-60 or HEK293 cells. Pancreas and Liver.

    Known Application: Western Blot (0.5-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    Frataxin (FXN)
    别名
    FXN (FXN 产品)
    别名
    zgc:158218 antibody, LOC100284365 antibody, BcDNA:AT09528 antibody, CG8971 antibody, DFH antibody, Dfh antibody, Dmel\\CG8971 antibody, X25 antibody, dfh antibody, CyaY antibody, FA antibody, FARR antibody, FRDA antibody, RGD1565754 antibody, Frda antibody, frataxin antibody, fxn antibody, LOC100284365 antibody, TVAG_182150 antibody, fh antibody, FTX1 antibody, FXN antibody, Fxn antibody
    背景
    Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), a human autosomal recessive neurodegenerative disease. Lack of Frataxin causes iron to accumulate in the mitochondrial matrix suggesting that Frataxin is involved in mitochondrial iron homeostasis and possibly in iron transport. Frataxin has an alpha-beta fold consisting of two helices flanking an antiparallel beta sheet.
    分子量
    14kDa
    基因ID
    2395
    UniProt
    Q16595
    途径
    Transition Metal Ion Homeostasis, Regulation of Cell Size
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