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FcRn 抗体 (AA 24-215)

FcRn 适用: 人 IHC, ISt, StM 宿主: 小鼠 Monoclonal FCGRT-2932 unconjugated
产品编号 ABIN6939380
发货至: 中国
  • 抗原 See all FcRn 抗体
    FcRn (IgG receptor FcRn (FcRn))
    抗原表位
    • 14
    • 10
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 24-215
    适用
    • 42
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 39
    • 8
    • 1
    小鼠
    克隆类型
    • 40
    • 8
    单克隆
    标记
    • 23
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FcRn antibody is un-conjugated
    应用范围
    • 30
    • 28
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), Immunostaining (ISt), Staining Methods (StM)
    纯化方法
    Purified by Protein A/G
    免疫原
    Recombinant fragment of human FCGRT protein (around aa 24-215) (Exact sequence is proprietary)
    克隆位点
    FCGRT-2932
    亚型
    IgG2b kappa
    Top Product
    Discover our top product FcRn Primary Antibody
  • 应用备注

    Positive Control: THP1 or HepG2 cells. Cerebellum or Testis.

    Known Application: Immunohistochemistry (Formalin-fixed) (2-4 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    FcRn (IgG receptor FcRn (FcRn))
    别名
    FCGRT (FcRn 产品)
    别名
    FCRN antibody, alpha-chain antibody, FcRn antibody, Fc fragment of IgG receptor and transporter antibody, Fc receptor, IgG, alpha chain transporter antibody, FCGRT antibody, Fcgrt antibody
    背景
    This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. FCGRT is present in the intestinal epithelium of neonates and mediates the selective uptake of immunoglobulin G (IgG) in mothers' milk, thereby helping newborn to acquire passive immunity. FCGRT is comprised of a heavy chain and -2-Microglobulin. FCGRT localizes in endosomes of vascular endothelial cells and selectively recycles IgG to the cell surface, thus protecting IgG from lysosomal degradation.
    分子量
    46kDa
    基因ID
    2217
    UniProt
    P55899
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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