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ERCC1 抗体 (AA 191-281)

ERCC1 适用: 人 WB, ELISA, Coat 宿主: 小鼠 Monoclonal ERCC1-2683 unconjugated
产品编号 ABIN6939334
发货至: 中国
  • 抗原 See all ERCC1 抗体
    ERCC1 (Excision Repair Cross Complementing Polypeptide-1 (ERCC1))
    抗原表位
    • 15
    • 11
    • 10
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 191-281
    适用
    • 86
    • 35
    • 24
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 59
    • 25
    • 2
    小鼠
    克隆类型
    • 60
    • 26
    单克隆
    标记
    • 52
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ERCC1 antibody is un-conjugated
    应用范围
    • 70
    • 42
    • 15
    • 13
    • 13
    • 12
    • 12
    • 8
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Coating (Coat)
    特异性
    Recognizes a protein of 110 kDa, identified as Excision Repair Cross Complementing 1 (ERCC1). It is a mammalian nucleotide excision repair (NER) enzyme involved in repair of damaged DNA. ERCC1 is a homologous to RAD10 in Saccharomyces cerevisiae, which is required in mitotic intrachromosomal recombination and repair. ERCC1 is required in repair of cisplatin-induced DNA adducts and ultraviolet (UV)-induced DNA damage. High expression of ERCC1 has been linked to tumor progression in a variety of cancers including non-small cell lung cancer (NSCLC), squamous cell carcinoma of the head, ovarian cancer and esophageal cancer.
    纯化方法
    Purified by Protein A/G
    免疫原
    Recombinant fragment (around aa 191-281) of human ERCC1 protein (exact sequence is proprietary)
    克隆位点
    ERCC1-2683
    亚型
    IgG1 kappa
    Top Product
    Discover our top product ERCC1 Primary Antibody
  • 应用备注

    Positive Control: HeLa, HepG2 cells. Tonsil.

    Known Application: ELISA (For coating, order Ab without BSA), Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    ERCC1 (Excision Repair Cross Complementing Polypeptide-1 (ERCC1))
    别名
    ERCC1 (ERCC1 产品)
    别名
    COFS4 antibody, RAD10 antibody, UV20 antibody, Ercc-1 antibody, ercc1 antibody, T12H1.18 antibody, T12H1_18 antibody, UV REPAIR DEFICIENT 7 antibody, UVR7 antibody, ERCC excision repair 1, endonuclease non-catalytic subunit antibody, excision repair cross-complementing rodent repair deficiency, complementation group 1 antibody, DNA excision repair protein ERCC-1 antibody, nucleotide repair protein antibody, excision repair cross-complementation group 1 L homeolog antibody, excision repair cross-complementation group 1 antibody, ERCC1 antibody, Ercc1 antibody, CC1G_04546 antibody, CpipJ_CPIJ013903 antibody, PITG_13719 antibody, ercc1 antibody, ercc1.L antibody
    分子量
    110kDa
    基因ID
    2067
    UniProt
    P07992
    途径
    DNA Damage Repair, Production of Molecular Mediator of Immune Response
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