ERCC1 抗体 (AA 191-281)
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- 抗原 See all ERCC1 抗体
- ERCC1 (Excision Repair Cross Complementing Polypeptide-1 (ERCC1))
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抗原表位
- AA 191-281
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ERCC1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Coating (Coat)
- 特异性
- Recognizes a protein of 110 kDa, identified as Excision Repair Cross Complementing 1 (ERCC1). It is a mammalian nucleotide excision repair (NER) enzyme involved in repair of damaged DNA. ERCC1 is a homologous to RAD10 in Saccharomyces cerevisiae, which is required in mitotic intrachromosomal recombination and repair. ERCC1 is required in repair of cisplatin-induced DNA adducts and ultraviolet (UV)-induced DNA damage. High expression of ERCC1 has been linked to tumor progression in a variety of cancers including non-small cell lung cancer (NSCLC), squamous cell carcinoma of the head, ovarian cancer and esophageal cancer.
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Recombinant fragment (around aa 191-281) of human ERCC1 protein (exact sequence is proprietary)
- 克隆位点
- ERCC1-2683
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product ERCC1 Primary Antibody
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- 应用备注
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Positive Control: HeLa, HepG2 cells. Tonsil.
Known Application: ELISA (For coating, order Ab without BSA), Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- ERCC1 (Excision Repair Cross Complementing Polypeptide-1 (ERCC1))
- 别名
- ERCC1 (ERCC1 产品)
- 别名
- COFS4 antibody, RAD10 antibody, UV20 antibody, Ercc-1 antibody, ercc1 antibody, T12H1.18 antibody, T12H1_18 antibody, UV REPAIR DEFICIENT 7 antibody, UVR7 antibody, ERCC excision repair 1, endonuclease non-catalytic subunit antibody, excision repair cross-complementing rodent repair deficiency, complementation group 1 antibody, DNA excision repair protein ERCC-1 antibody, nucleotide repair protein antibody, excision repair cross-complementation group 1 L homeolog antibody, excision repair cross-complementation group 1 antibody, ERCC1 antibody, Ercc1 antibody, CC1G_04546 antibody, CpipJ_CPIJ013903 antibody, PITG_13719 antibody, ercc1 antibody, ercc1.L antibody
- 分子量
- 110kDa
- 基因ID
- 2067
- UniProt
- P07992
- 途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
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