Desmoglein 3 抗体 (AA 379-491)
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- 抗原 See all Desmoglein 3 (DSG3) 抗体
- Desmoglein 3 (DSG3)
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抗原表位
- AA 379-491
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Desmoglein 3 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Staining Methods (StM)
- 特异性
- Recognizes a protein of 130 kDa, identified as Desmoglein-3 (DSG3). This MAb is highly specific to Desmoglein-3 and does not cross-react with other members of the Desmoglein-family. DSG3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Research has shown that DSG3 has a very high sensitivity (80 % ) and specificity (100 %) in recognizing squamous cell carcinoma (SqCC). Therefore, DSG3 is considered a very important marker for lung SqCC and can be a useful ancillary marker to separate SqCC from other subtypes of lung cancer. Moreover, studies have shown that DSG3 expression in lung SqCC may indicate a poor prognosis.
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Recombinant fragment (around aa 379-491) human DSG3 protein (exact sequence is proprietary)
- 克隆位点
- DSG3-2840
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product DSG3 Primary Antibody
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anti-Desmoglein 3 (DSG3) (AA 55-159) antibody
DSG3 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 6G2C11 unconjugated
anti-Desmoglein 3 (DSG3) (AA 858-999) antibodyDSG3 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Desmoglein 3 (DSG3) (AA 379-491) antibodyDSG3 适用: 人 IHC 宿主: 小鼠 Monoclonal MSVA-543M unconjugated
anti-Desmoglein 3 (DSG3) (AA 50-75) antibodyDSG3 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Desmoglein 3 (DSG3) (AA 70-615) antibodyDSG3 适用: 人 ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Desmoglein 3 (DSG3) (AA 379-491) antibodyDSG3 适用: 人 WB, ELISA, Coat 宿主: 小鼠 Monoclonal DSG3-2796 unconjugated
anti-Desmoglein 3 (DSG3) antibodyDSG3 适用: 人 WB, IF, IHC, FACS, StM 宿主: 小鼠 Monoclonal 5G11 unconjugated
anti-Desmoglein 3 (DSG3) antibodyDSG3 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Desmoglein 3 (DSG3) (AA 334-604) antibodyDSG3 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C8 unconjugated
anti-Desmoglein 3 (DSG3) (AA 50-615) antibodyDSG3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Positive Control: A431 cells. Skin or Lung Squamous Cell Carcinoma (SCC).
Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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