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Dystrophin 抗体 (AA 114-263)

DMD 适用: 人 IHC, ELISA, Coat, StM 宿主: 小鼠 Monoclonal DMD-3242 unconjugated
产品编号 ABIN6939242
发货至: 中国
  • 抗原 See all Dystrophin (DMD) 抗体
    Dystrophin (DMD)
    抗原表位
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 114-263
    适用
    • 54
    • 26
    • 25
    • 5
    • 1
    宿主
    • 39
    • 16
    小鼠
    克隆类型
    • 30
    • 25
    单克隆
    标记
    • 28
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    This Dystrophin antibody is un-conjugated
    应用范围
    • 21
    • 19
    • 13
    • 10
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC), ELISA, Coating (Coat), Staining Methods (StM)
    纯化方法
    Purified by Protein A/G
    免疫原
    A recombinant fragment (around aa 114-263) of human DMD protein (exact sequence is proprietary)
    克隆位点
    DMD-3242
    亚型
    IgG2b kappa
    Top Product
    Discover our top product DMD Primary Antibody
  • 应用备注

    Positive Control: Human skeletal muscle and heart muscle tissues (IHC).

    Known Application: ELISA (For coating, order Ab without BSA),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    Dystrophin (DMD)
    别名
    DMD (DMD 产品)
    别名
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    背景
    Dystrophin-glycoprotein complex (DGC) connects the F-Actin cytoskeleton on the inner surface of muscle fibers to the surrounding extracellular matrix, through the cell membrane interface. A deficiency in this protein contributes to Duchenne (DMD) and Becker (BMD) muscular dystrophies. The human dystrophin gene measures 2.4 megabases, has more than 80 exons, produces a 14 kb mRNA and contains at least 8 independent tissue-specific promoters and 2 poly A sites. The dystrophin mRNA can undergo differential splicing and produce a range of transcripts that encode a large set of proteins. Dystrophin represents approximately 0.002 % of total striated muscle protein and localizes to triadic junctions in skeletal muscle, where it is thought to influence calcium ion homeostasis and force transmission.
    分子量
    427kDa
    基因ID
    1756
    UniProt
    P11532
    途径
    Skeletal Muscle Fiber Development
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