DBN1 抗体 (AA 150-281)
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- 抗原 See all DBN1 抗体
- DBN1 (Drebrin 1 (DBN1))
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抗原表位
- AA 150-281
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This DBN1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Staining Methods (StM)
- 免疫原
- Recombinant fragment (aa 150-281) of human DBN1 protein (exact sequence is proprietary)
- 克隆位点
- DBN1-2879
- 亚型
- IgG1 kappa
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- 应用备注
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Positive Control: Brain neurons. Also found in the heart, placenta, skeletal muscle, kidney and pancreas.
Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1.0 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- DBN1 (Drebrin 1 (DBN1))
- 别名
- DBN1 (DBN1 产品)
- 别名
- D0S117E antibody, DBN1 antibody, LOC733967 antibody, drebrin 1 antibody, drebrin 1 S homeolog antibody, DBN1 antibody, Dbn1 antibody, dbn1.S antibody, dbn1 antibody
- 背景
- Drebrins (developmentally regulated brain proteins) are cytoplasmic proteins that bind F-actin in the brain and are involved in cell migration, extension of neuronal processes and plasticity of dendrites. There are three isoforms: two embryonic types (E1 and E2), and an adult type (A), generated by alternative RNA splicing from a single Drebrin gene. Drebrins are expressed mainly in brain neurons but are also found in skeletal muscle, heart, placenta, pancreas and kidney. Drebrin has been designated as a marker of the dendritic spine. Decreases in Drebrin levels in the brain have been been associated with Alzheimer s disease and Down syndrome.
- 分子量
- 120kDa
- 基因ID
- 1627
- UniProt
- Q16643
- 途径
- Maintenance of Protein Location
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