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CNN1 抗体

CNN1 适用: 人, 大鼠 FACS, IF, IHC, WB, StM 宿主: 小鼠 Monoclonal CALP unconjugated
产品编号 ABIN6939161
发货至: 中国
  • 抗原 See all CNN1 抗体
    CNN1 (Calponin 1 (CNN1))
    适用
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    人, 大鼠
    宿主
    • 56
    • 35
    • 2
    小鼠
    克隆类型
    • 51
    • 42
    单克隆
    标记
    • 38
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    This CNN1 antibody is un-conjugated
    应用范围
    • 58
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    Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB), Staining Methods (StM)
    特异性
    Multiple isoelectric variants of calponin have been identified, however only two molecular weight isoforms exist, a 34 kDa form and a 29 kDa form. Expression of the 29 kDa form, I-calponin, is primarily restricted to muscle of the urogenital tract, whereas the higher molecular weight variant has been demonstrated in vascular and visceral smooth muscle. In Western blotting, this MAb reacts with only the 34 kDa form of calponin in extracts of human aortic medial smooth muscle and is unreactive with fibroblast extracts of cultivated human foreskin. Calponin is a calmodulin, F-actin and tropomyosin binding protein, which is thought to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing smooth muscle.
    纯化方法
    Purified by Protein A/G
    免疫原
    Crude human uterus extract
    克隆位点
    CALP
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CNN1 Primary Antibody
  • 应用备注

    Positive Control: K562 cells, Myoepithelial cells in breast ducts.

    Known Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 1 mM EDTA, pH 7.5-8.5, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    CNN1 (Calponin 1 (CNN1))
    别名
    CNN1 (CNN1 产品)
    别名
    CN antibody, CnnI antibody, SMCC antibody, Sm-Calp antibody, XclpH3 antibody, clpH3 antibody, cnn2 antibody, calponin 1 antibody, calponin 1, basic, smooth muscle L homeolog antibody, cnn1 antibody, Cnn1 antibody, CNN1 antibody, cnn1.L antibody
    分子量
    34kDa
    基因ID
    1264
    UniProt
    P51911
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