UPK1A 抗体 (AA 114-173)
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- 抗原 See all UPK1A 抗体
- UPK1A (Uroplakin 1a (UPK1A))
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抗原表位
- AA 114-173
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This UPK1A antibody is un-conjugated
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应用范围
- ELISA, Coating (Coat), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression.
- 交叉反应 (详细)
- Human,
- 纯化方法
- 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
- 免疫原
- Recombinant fragment (around aa 114-173) of human Uroplakin 1A (UPK1A) protein (exact sequence is proprietary)
- 克隆位点
- UPK1A-2921
- 亚型
- IgG2b
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- 应用备注
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Positive Control: Urinary Bladder.
Known Application: ELISA (For coating, order Ab without BSA), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.
- 有效期
- 24 months
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- 抗原
- UPK1A (Uroplakin 1a (UPK1A))
- 别名
- UPK1A (UPK1A 产品)
- 别名
- up1a antibody, upia antibody, upka antibody, tspan21 antibody, MGC81390 antibody, upk1a antibody, MGC69509 antibody, UPK1A antibody, wu:fb14a02 antibody, wu:fk84c04 antibody, zgc:136832 antibody, TSPAN21 antibody, UP1A antibody, UPIA antibody, UPKA antibody, 1110031P12Rik antibody, AU019298 antibody, C87192 antibody, Tspan21 antibody, Upk1 antibody, uroplakin 1A antibody, uroplakin 1A L homeolog antibody, uroplakin 1a antibody, UPK1A antibody, upk1a.L antibody, upk1a antibody, Upk1a antibody
- 背景
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UP1A, UPIA, UPKA, TSPAN21,Uroplakin 1A (Urothelial Differentiation Marker)
Cellular localisation: Cell Surface - 分子量
- 29kDa
- 基因ID
- 11045, 159309
- UniProt
- O00322
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