Recombinant CGB 抗体
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- 抗原 See all CGB 抗体
- CGB (Chorionic Gonadotropin, beta Polypeptide (CGB))
- 抗体类型
- Recombinant Antibody
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CGB antibody is un-conjugated
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应用范围
- Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- This MAb reacts with a protein of 22 kDa, identified as beta sub-unit of HCG. It does not cross react with the alpha sub-unit. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the subunit is identical to that of thyroid stimulating hormone (TSH) follicle stimulating hormone (FSH), and luteinizing hormone (LH). hCG MAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90 % and 60 % of cases respectively. 20 % of lung squamous cell carcinomas are positive. hCG expression by non-trophoblastic tumors may indicate aggressive behavior.
- 交叉反应 (详细)
- Human,
- 纯化方法
- 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
- 免疫原
- Recombinant full-length human hCG beta protein
- 克隆位点
- RHCGb-54
- 亚型
- IgG1
- Top Product
- Discover our top product CGB Primary Antibody
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- 应用备注
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Positive Control: JAR or TT cells. Placenta.
Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL, 30 min RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.
- 有效期
- 24 months
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- 抗原
- CGB (Chorionic Gonadotropin, beta Polypeptide (CGB))
- 别名
- CGB (CGB 产品)
- 别名
- CGB antibody, CGB3 antibody, CGB5 antibody, CGB7 antibody, CGB8 antibody, hCGB antibody, CG-beta antibody, chorionic gonadotropin, beta polypeptide antibody, chorionic gonadotropin beta subunit 3 antibody, CGB antibody, CGB3 antibody
- 背景
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CG-beta, CGB3, CGB5, CGB7, CGB8, Choriogonadotropin Subunit beta, hCGB,HCG-beta (Pregnancy & Choriocarcinoma Marker)
Cellular localisation: Cytoplasmic, secreted - 分子量
- 22kDa
- 基因ID
- 1082, 172944
- UniProt
- P01233
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