OLIG2 抗体 (AA 1-141)
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- 抗原 See all OLIG2 抗体
- OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))
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抗原表位
- AA 1-141
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This OLIG2 antibody is un-conjugated
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应用范围
- Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- Olig2, a basic helix-loop-helix transcription factor, is involved in oligodendroglial specification. Olig2 expression has been reported in most glial tumors, such as oligodendrogliomas and astrocytomas. Although more than half of glioblastomas are positive for Olig2, expression is very weak in terms of both percentage of labeled cells and intensity. No Olig2 expression has been found in the non-glial tumors including neuro-epithelial tumors, ependymomas, sub-ependymomas, medulloblastomas, and non-neuroepithelial tumors, such as CNS lymphomas, meningiomas, schwannomas, atypical teratoid / rhabdoid tumor, and haemangioblastomas. Compared to the strong staining seen in glioma samples, a weak expression is observed in non-tumoral brain tissue (gliosis).
- 交叉反应 (详细)
- Human,
- 纯化方法
- 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
- 免疫原
- Recombinant fragment of human OLIG2 protein (around aa 1-141) (exact sequence is proprietary)
- 克隆位点
- OLIG2-2400
- 亚型
- IgG1
- Top Product
- Discover our top product OLIG2 Primary Antibody
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- 应用备注
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Positive Control: THP-1 cells. Astrocytoma.
Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.
- 有效期
- 24 months
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- 抗原
- OLIG2 (Oligodendrocyte Lineage Transcription Factor 2 (OLIG2))
- 别名
- OLIG2 (OLIG2 产品)
- 别名
- olig3.2 antibody, MGC89336 antibody, OLIG2 antibody, BHLHB1 antibody, OLIGO2 antibody, PRKCBP2 antibody, RACK17 antibody, bHLHe19 antibody, wu:fc64g09 antibody, AI604895 antibody, Bhlhb1 antibody, Olg-2 antibody, Oligo2 antibody, RK17 antibody, oligodendrocyte transcription factor 4 antibody, oligodendrocyte transcription factor 2 antibody, oligodendrocyte lineage transcription factor 2 antibody, olig4 antibody, OLIG2 antibody, Olig2 antibody, olig2 antibody
- 背景
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Basic helix loop helix protein class B1 (bHLHB1), basic helix-loop-helix protein 19 (bHLHe19), OLIG2, Oligodendrocyte lineage transcription factor 2, Oligodendrocyte specific bHLH transcription factor 2, Oligodendrocyte transcription factor 2, Protein kinase C-binding protein 2 (PRKCBP2), RACK17,OLIG2 (Marker of Glial Brain Tumors)
Cellular localisation: Nuclear - 分子量
- 30-40kDa
- 基因ID
- 10215, 176977
- UniProt
- Q13516
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