LI Cadherin 抗体 (AA 242-418)
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- 抗原 See all LI Cadherin 抗体
- LI Cadherin
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抗原表位
- AA 242-418
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This LI Cadherin antibody is un-conjugated
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应用范围
- Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Flow Cytometry (FACS)
- 特异性
- It recognizes a protein of 120 kDa, which is identified as Cadherin 17 (also known as LI Cadherin). The cadherins are a family of Calcium-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including beta-catenin, to regulate cadherin function. LI-cadherin (for liver-intestine-cadherin) expression is restricted to liver and intestine tissues and is specifically localized to the basolateral domain of hepatocytes and enterocytes.
- 交叉反应 (详细)
- Human,
- 纯化方法
- 200ug/ml of Ab Purified from rabbit anti-serum by Protein A.
- 免疫原
- Recombinant fragment (around aa 242-418) of human Cadherin 17 protein (CDH17) (exact sequence is proprietary)
- 克隆位点
- CDH17-2618
- 亚型
- IgG2b
- Top Product
- Discover our top product LI Cadherin Primary Antibody
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- 应用备注
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Positive Control: MCF-7, HepG2 or HT29 cells. Stomach, Small Intestine, Colon or liver.
Known Application: Flow Cytometry (1-2 μg/million cells),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.
- 有效期
- 24 months
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- 抗原
- LI Cadherin
- 别名
- CDH17 (LI Cadherin 产品)
- 别名
- CDH16 antibody, HPT-1 antibody, HPT1 antibody, HPT-1/LI antibody, cb903 antibody, fb65d02 antibody, wu:fb65d02 antibody, cadherin-17 antibody, cadherin 17 antibody, cadherin 17, LI cadherin (liver-intestine) antibody, CDH17 antibody, Cdh17 antibody, cdh17 antibody
- 背景
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BILL-cadherin, Cadherin-17, CDH17, HPT-1 cadherin, human intestinal peptide-associated transporter HPT-1, human peptide transporter 1 (HPT-1), Intestinal peptide-associated transporter HPT-1, LI-cadherin (liver-intestine), Liver Cadherin, Liver-intestine cadherin,Cadherin 17 / LI Cadherin (Liver-Intestine Marker)
Cellular localisation: Cell Surface and Cytoplasmic - 分子量
- 120kDa
- 基因ID
- 1015, 591853
- UniProt
- Q12864
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