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Cadherin-16 抗体 (AA 371-507)

CDH16 适用: 人 ELISA, IHC (f), Coat 宿主: 小鼠 Monoclonal CDH16-2448 unconjugated
产品编号 ABIN6939023
发货至: 中国
  • 抗原 See all Cadherin-16 (CDH16) 抗体
    Cadherin-16 (CDH16)
    抗原表位
    • 8
    • 8
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 371-507
    适用
    • 88
    • 40
    • 31
    • 22
    • 21
    • 1
    • 1
    • 1
    宿主
    • 55
    • 34
    • 1
    小鼠
    克隆类型
    • 47
    • 43
    单克隆
    标记
    • 51
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Cadherin-16 antibody is un-conjugated
    应用范围
    • 42
    • 38
    • 37
    • 37
    • 25
    • 19
    • 12
    • 6
    • 4
    • 3
    • 1
    • 1
    ELISA, Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Coating (Coat)
    特异性
    This MAb recognizes a protein of 130 kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels.Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
    交叉反应 (详细)
    Human,
    纯化方法
    200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
    免疫原
    Recombinant fragment (around aa 371-507) of human CDH16 protein (exact sequence is proprietary)
    克隆位点
    CDH16-2448
    亚型
    IgG2b
    Top Product
    Discover our top product CDH16 Primary Antibody
  • 应用备注

    Positive Control: Normal kidney or renal cell carcinoma.

    Known Application: ELISA (For coating, order Ab without BSA),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.
    有效期
    24 months
  • 抗原
    Cadherin-16 (CDH16)
    别名
    CDH16 (CDH16 产品)
    别名
    cadherin 16 antibody, CDH16 antibody, Cdh16 antibody
    背景
    Cadherin-16 (CDH16), Kidney-specific cadherin, Ksp-cadherin antibody,Ksp-Cadherin / CDH16 (Renal Cell Marker)
    Cellular localisation: Cell Surface and Cytoplasmic
    分子量
    130kDa
    基因ID
    1014, 513660
    UniProt
    O75309
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