ZFYVE28 抗体
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- 抗原 See all ZFYVE28 抗体
- ZFYVE28 (Zinc Finger, FYVE Domain Containing 28 (ZFYVE28))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ZFYVE28 antibody is un-conjugated
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应用范围
- Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- ZFYVE28 belongs to the lst-2 family. It contains 1 FYVE-type zinc finger. The FYVE-type zinc finger mediates the interaction with phosphatidylinositol 3-phosphate (PI3P) and localization to early endosome membranes when not mono-ubiquitinated at Lys-87. Mono-ubiquitination at Lys-87 prevents binding to phosphatidylinositol 3-phosphate (PI3P) and localization to early endosome membranes. ZFYVE28 is a negative regulator of epidermal growth factor receptor (EGFR) signaling. It acts by promoting EGFR degradation in endosomes when not mono-ubiquitinated. The FYVE domain has been identified in a number of unrelated signaling molecules. This protein functions to recruit SMAD2 to the transforming growth factor-beta receptor. The FYVE domain is required to maintain the normal localization of this protein but is not involved in mediating interaction with SMADs.
- 交叉反应 （详细）
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant full-length human ZFYVE28 protein
- 克隆位点
- LST2-2426
- 亚型
- IgG2a kappa
- Top Product
- Discover our top product ZFYVE28 Primary Antibody
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anti-Zinc Finger, FYVE Domain Containing 28 (ZFYVE28) antibody
ZFYVE28 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal LST2-2426 unconjugated
anti-Zinc Finger, FYVE Domain Containing 28 (ZFYVE28) (AA 1-887) antibodyZFYVE28 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Zinc Finger, FYVE Domain Containing 28 (ZFYVE28) (AA 131-180) antibodyZFYVE28 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, FYVE Domain Containing 28 (ZFYVE28) (N-Term) antibodyZFYVE28 适用: 人, 小鼠, 大鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, FYVE Domain Containing 28 (ZFYVE28) (AA 604-633), (C-Term) antibodyZFYVE28 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, FYVE Domain Containing 28 (ZFYVE28) (AA 611-642), (C-Term) antibodyZFYVE28 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (0.1-0.2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: PC3 cells. Testis, Brain, Colon, Kidney or Stomach.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- ZFYVE28 (Zinc Finger, FYVE Domain Containing 28 (ZFYVE28))
- 别名
- ZFYVE28 (ZFYVE28 产品)
- 别名
- LST2 antibody, LYST2 antibody, 9630058O20Rik antibody, Gm146 antibody, mKIAA1643 antibody, id:ibd1374 antibody, zgc:152894 antibody, zinc finger FYVE-type containing 28 antibody, zinc finger, FYVE domain containing 28 antibody, ZFYVE28 antibody, Zfyve28 antibody, zfyve28 antibody
- 背景
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Lateral signaling target protein 2 homolog, LST2, LYST2, Zinc finger FYVE domain-containing protein 28 (ZFYVE28),ZFYVE28 (Zinc Finger FYVE-type containing 28)
Cellular localisation: Cytoplasmic - 分子量
- 96kDa
- 基因ID
- 57732, 292056
- 途径
- EGFR Signaling Pathway
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