VLDLR 抗体 (C-Term)
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- 抗原 See all VLDLR 抗体
- VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This VLDLR antibody is un-conjugated
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应用范围
- Immunostaining (ISt), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- VLDLR (very low density lipoprotein receptor) is a member of the LDL receptor gene family, which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. VLDLR associates with RAP (receptor associated protein) during receptor folding, and RAP facilitates the secretion of the extracellular region of VLDLR. VLDLR is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development.
- 交叉反应 (详细)
- Human. Rat.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant human VLDLR fragment from c-terminal
- 克隆位点
- VLDLR-1337
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product VLDLR Primary Antibody
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- 应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues is enhanced by heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0 for 45 min at 95°C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or U-251 cells. Pancreas, Cerebellum, Heart or Skeletal Muscle.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))
- 别名
- VLDLR (VLDLR 产品)
- 背景
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Very low-density lipoprotein receptor, VLDL receptor, VLDL-R, VLDLR,VLDL-Receptor (Very Low Density Lipoprotein Receptor)
Cellular localisation: Cytoplasmic - 分子量
- 143-161kDa
- 基因ID
- 7436, 370422
- UniProt
- P98155
- 途径
- Cellular Response to Molecule of Bacterial Origin
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