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Recombinant Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) 抗体

SPTBN2 适用: 人 WB, FACS, ELISA, Coat, IHC (f) 宿主: 兔 Monoclonal SPTBN2-2894R unconjugated Recombinant Antibody
产品编号 ABIN6938449
发货至: 中国
  • 抗原 See all Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) 抗体
    Spectrin, Beta, Non-erythrocytic 2 (SPTBN2)
    抗体类型
    Recombinant Antibody
    抗原表位
    • 49
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 356-475
    适用
    • 60
    • 23
    • 21
    • 1
    宿主
    • 44
    • 16
    克隆类型
    • 51
    • 9
    单克隆
    标记
    • 32
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    非结合性
    应用范围
    • 58
    • 45
    • 44
    • 42
    • 18
    • 13
    • 7
    • 4
    • 4
    • 3
    Western Blotting (WB), Flow Cytometry (FACS), ELISA, Coating (Coat), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    Spectrin is an actin binding protein that is a major component of the plasma membrane skeleton. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Vertebrate spectrins have two alpha-subunits (alpha-I/alpha-II) four beta-subunits (beta-I-beta-IV) and a beta-H subunit creating diversity and specialization of function. Spectrin III is highly expressed in brain, kidney, pancreas and liver, and at lower levels in lung and placenta. Spectrin beta 3 is primarily expressed in nervous tissues with highest expression levels in the cerebellum, where it is found in Purkinje cell soma and dendrites.
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant human SPTBN2 fragment (aa356-475) (exact sequence is proprietary)
    克隆位点
    SPTBN2-2894R
    亚型
    IgG
    Top Product
    Discover our top product SPTBN2 Primary Antibody
  • 应用备注

    Known_Application: Flow Cytometry (1-2 μg/million cells), (ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA),Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa cells. Pancreas or Liver.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    Spectrin, Beta, Non-erythrocytic 2 (SPTBN2)
    别名
    SPTBN2 (SPTBN2 产品)
    别名
    Spnb3 antibody, mKIAA0302 antibody, GTRAP41 antibody, SCA5 antibody, spectrin beta, non-erythrocytic 2 antibody, spectrin, beta, non-erythrocytic 2 antibody, Sptbn2 antibody, SPTBN2 antibody
    背景
    Beta III spectrin, SCA5, Spectrin beta chain brain 2, Spectrin beta non-erythrocytic 2, Spectrin non-erythroid beta chain 2, Spinocerebellar ataxia 5, SPTBN2,Spectrin beta III (SPTBN2)
    Cellular localisation: Cell Surface
    分子量
    246kDa
    基因ID
    6712, 26915
    UniProt
    O15020
    途径
    Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis
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