S100A8 抗体
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- 抗原 See all S100A8 抗体
- S100A8 (S100 Calcium Binding Protein A8 (S100A8))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This S100A8 antibody is un-conjugated
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应用范围
- Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- Recognizes the L1 or Calprotectin molecule, an intra-cytoplasmic antigen comprising of a 12kDa alpha chain and a 14kDa beta chain expressed by granulocytes, monocytes and by tissue macrophages. Macrophages usually arise from hematopoietic stem cells in the bone marrow. Under migration into tissues, the monocytes undergo further differentiation to become multifunctional tissue macrophages. They are classified into normal and inflammatory macrophages. Normal macrophages include macrophages in connective tissue (histiocytes), liver (Kupffer's cells), lung (alveolar macrophages), lymph nodes (free and fixed macrophages), spleen (free and fixed macrophages), bone marrow (fixed macrophages), serous fluids (pleural and peritoneal macrophages), skin (histiocytes, Langerhans's cell) and in other tissues. Inflammatory macrophages are present in various exudates. Macrophages are part of the innate immune system, recognizing, engulfing and destroying many potential pathogens including bacteria, pathogenic protozoa, fungi and helminthes. This MAb reacts with neutrophils, monocytes, macrophages, and squamous mucosal epithelia and has been shown as an important marker for identifying macrophages in tissue sections.
- 交叉反应 （详细）
- Human. Baboon. Monkey. Cow. Pig. Goat. Horse. Cat. Dog. Rabbit. Guinea Pig. Rat. Mouse.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Affinity Purified monocyte membrane preparation
- 克隆位点
- MRP8 7C12-4
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product S100A8 Primary Antibody
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anti-S100 Calcium Binding Protein A8 (S100A8) (AA 1-89) antibody
S100A8 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-S100 Calcium Binding Protein A8 (S100A8) (AA 1-89) antibodyS100A8 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-S100 Calcium Binding Protein A8 (S100A8) (AA 1-93) antibodyS100A8 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-S100 Calcium Binding Protein A8 (S100A8) (AA 1-93) antibodyS100A8 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C6 unconjugated
anti-S100 Calcium Binding Protein A8 (S100A8) (AA 1-93) antibodyS100A8 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-S100 Calcium Binding Protein A8 (S100A8) antibodyS100A8 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-S100 Calcium Binding Protein A8 (S100A8) antibodyS100A8 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-S100 Calcium Binding Protein A8 (S100A8) antibodyS100A8 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-S100 Calcium Binding Protein A8 (S100A8) antibodyS100A8 适用: 人, 小鼠, 大鼠, Cow, Pig, 兔, Cat, 犬, 猴, 马, 豚鼠, Baboon, 山羊 IHC, StM 宿主: 兔 Monoclonal MAC3157R unconjugated Recombinant Antibody
anti-S100 Calcium Binding Protein A8 (S100A8) antibodyS100A8 适用: 人, 小鼠, 大鼠, Cow, Pig, 兔, Cat, 犬, 猴, 马, 豚鼠, Baboon, 山羊 IHC, StM 宿主: 小鼠 Monoclonal rMAC3781 unconjugated Recombinant Antibody
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- 应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Tonsil, lymph node or spleen.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- S100A8 (S100 Calcium Binding Protein A8 (S100A8))
- 别名
- S100A8 (S100A8 产品)
- 别名
- 60B8AG antibody, CAGA antibody, CFAG antibody, CGLA antibody, CP-10 antibody, L1Ag antibody, MA387 antibody, MIF antibody, MRP8 antibody, NIF antibody, P8 antibody, Mrp8 antibody, S100A8 antibody, 60B8Ag antibody, AI323541 antibody, B8Ag antibody, CFAg antibody, Caga antibody, p8 antibody, MRP-8 antibody, S100 calcium binding protein A8 antibody, S100 calcium binding protein A8 (calgranulin A) antibody, S100A8 antibody, S100a8 antibody
- 背景
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60B8AG, Calgranulin A (CAGA), Calgranulin B (CAGB), Calprotectin L1L subunit, Chemotactic cytokine CP-10, Cystic fibrosis antigen (CFAG), Leukocyte L1 complex light chain, L1Ag, Macrophage L1 protein Calprotectin, Migration inhibitory factor related protein 8, Myeloid-related protein 8 (MRP-8 or P8), Myeloid-related protein 14 (MRP-14 or P14), Neutrophil cytosolic 7 kDa protein, NIF, S100A8/S100A9 complex, MA387, Pro-inflammatory S100 cytokine, Urinary stone protein band A,Calprotectin / MRP14 / S100A9 / Calgranulin B
Cellular localisation: Cytoplasmic - 分子量
- MAC387
- 基因ID
- 6279, 6280, 416073
- UniProt
- P05109, P06702
- 途径
- Transition Metal Ion Homeostasis, Positive Regulation of Endopeptidase Activity, S100 Proteins
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