PMEPA1 抗体
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- 抗原 See all PMEPA1 抗体
- PMEPA1 (Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PMEPA1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- PMEPA1 (prostate transmembrane protein, androgen induced 1 is a 287 amino acid single-pass membrane protein that contains WW-binding motifs and localizes to the cell membrane. Expressed at high levels in prostate, kidney and ovary, PMEPA1 interacts with NEDD4 and may play a role in regulating AR (androgen receptor) levels, specifically in prostate cells. Down regulation of PMEPA1 is observed in prostate tumors, suggesting that PMEPA1 may exhibit activity as a tumor suppressor. Overexpression of this protein may play a role in multiple types of cancer.
- 交叉反应 (详细)
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant full-length human PMEPA1 protein
- 克隆位点
- PMEPA1-2697
- 亚型
- IgG kappa
- Top Product
- Discover our top product PMEPA1 Primary Antibody
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- 应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: SKBR-3 cells. Prostate, Breast or Renal Cell Carcinoma.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- PMEPA1 (Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))
- 别名
- PMEPA1 (PMEPA1 产品)
- 别名
- Tmepai antibody, PMEPA1 antibody, TMEPAI antibody, zgc:92731 antibody, tmepai antibody, STAG1 antibody, 2210418I02Rik antibody, AW455466 antibody, Erg1.2 antibody, N4wbp4 antibody, Stag1 antibody, prostate transmembrane protein, androgen induced 1 antibody, prostate transmembrane protein, androgen induced 1 L homeolog antibody, Pmepa1 antibody, PMEPA1 antibody, pmepa1 antibody, pmepa1.L antibody
- 背景
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PMEPA, PMEPA1, Prostate transmembrane protein, androgen induced 1, Solid tumor-associated 1 protein, STAG1, TMEPAI, Transmembrane prostate androgen-induced protein, Transmembrane, prostate androgen induced RNA,PMEPA1 / TMEPAI (Tumor Suppressor Oncoprotein)
Cellular localisation: Cell Surface and Cytoplasmic - 分子量
- 32kDa
- 基因ID
- 56937, 517155
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway
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