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PMEPA1 抗体

PMEPA1 适用: 人 IHC, IHC (f) 宿主: 小鼠 Monoclonal PMEPA1-2696 unconjugated
产品编号 ABIN6938198
发货至: 中国
  • 抗原 See all PMEPA1 抗体
    PMEPA1 (Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))
    适用
    • 19
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    宿主
    • 13
    • 6
    小鼠
    克隆类型
    • 12
    • 7
    单克隆
    标记
    • 17
    • 1
    • 1
    This PMEPA1 antibody is un-conjugated
    应用范围
    • 13
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    • 7
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    Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    PMEPA1 (prostate transmembrane protein, androgen induced 1 is a 287 amino acid single-pass membrane protein that contains WW-binding motifs and localizes to the cell membrane. Expressed at high levels in prostate, kidney and ovary, PMEPA1 interacts with NEDD4 and may play a role in regulating AR (androgen receptor) levels, specifically in prostate cells. Down regulation of PMEPA1 is observed in prostate tumors, suggesting that PMEPA1 may exhibit activity as a tumor suppressor. Overexpression of this protein may play a role in multiple types of cancer.
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant full-length human PMEPA1 protein
    克隆位点
    PMEPA1-2696
    亚型
    IgG1 kappa
    Top Product
    Discover our top product PMEPA1 Primary Antibody
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: Human prostate, breast or renal cell carcinoma tissue (IHC).

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    PMEPA1 (Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))
    别名
    PMEPA1 (PMEPA1 产品)
    别名
    Tmepai antibody, PMEPA1 antibody, TMEPAI antibody, zgc:92731 antibody, tmepai antibody, STAG1 antibody, 2210418I02Rik antibody, AW455466 antibody, Erg1.2 antibody, N4wbp4 antibody, Stag1 antibody, prostate transmembrane protein, androgen induced 1 antibody, prostate transmembrane protein, androgen induced 1 L homeolog antibody, Pmepa1 antibody, PMEPA1 antibody, pmepa1 antibody, pmepa1.L antibody
    背景
    PMEPA, PMEPA1, Prostate transmembrane protein, androgen induced 1, Solid tumor-associated 1 protein, STAG1, TMEPAI, Transmembrane prostate androgen-induced protein, Transmembrane, prostate androgen induced RNA,PMEPA1 / TMEPAI (Tumor Suppressor Oncoprotein)
    Cellular localisation: Cell surface. Cytoplasm.
    分子量
    32kDa
    基因ID
    56937, 517155
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway
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