Myogenin 抗体
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- 抗原 See all Myogenin (MYOG) 抗体
- Myogenin (MYOG) (Myogenin (Myogenic Factor 4) (MYOG))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Myogenin antibody is un-conjugated
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应用范围
- Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- Myogenin is a member of the MyoD family of myogenic basic helix-loop-helix (bHLH) transcription factors that also includes MyoD, Myf-5, and MRF4 (also known as herculinor Myf-6). MyoD family members are expressed exclusively in skeletal muscle and play a key role in activating myogenesis by binding to enhancer sequences of muscle-specific genes. The regulatory domain of MyoD is approximately 70 amino acids in length and includes both a basic DNA binding motif and a bHLH dimerization motif.MyoD family members share about 80% amino acid homology in their bHLH motifs.Anti-myogenin labels the nuclei of myoblasts in developing muscle tissue, and is expressed in tumor cell nuclei of rhabdomyosarcoma and some leiomyosarcomas. Positive nuclear staining may occur in Wilms' tumor.
- 交叉反应 (详细)
- Human. Mouse. Rat. Cat. Pig.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Human myogenin recombinant protein
- 克隆位点
- MGN185
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product MYOG Primary Antibody
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- 应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Rh-30 cells. Skeletal muscle or rhabdomyosarcoma.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- Myogenin (MYOG) (Myogenin (Myogenic Factor 4) (MYOG))
- 别名
- MYOG (MYOG 产品)
- 别名
- cb553 antibody, zgc:100763 antibody, LOC446037 antibody, myf4 antibody, Xmyog antibody, myogenin antibody, LOC100136471 antibody, LOC100224062 antibody, LOC100303673 antibody, MYF4 antibody, bHLHc3 antibody, myo antibody, myf-4 antibody, myogenin antibody, myogenin (myogenic factor 4) antibody, MYOG antibody, myog antibody, LOC100303673 antibody, Myog antibody
- 背景
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BHLHc3, cb553, Class C basic helix-loop-helix protein 3, Myf-4, MYF4, MYOG, Myogenic factor 4,Myogenin / Myf-4 (Skeletal Muscle Marker)
Cellular localisation: Nuclear - 分子量
- 34kDa
- 基因ID
- 4656, 2830
- UniProt
- P15173
- 途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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