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Recombinant MUC6 抗体

MUC6 适用: 人 IHC, IHC (f) 宿主: 兔 Monoclonal MUC6-1553R unconjugated Recombinant Antibody
产品编号 ABIN6937971
发货至: 中国
  • 抗原 See all MUC6 抗体
    MUC6 (Mucin 6, Oligomeric Mucus/gel-Forming (MUC6))
    抗体类型
    Recombinant Antibody
    适用
    • 49
    • 4
    • 1
    宿主
    • 29
    • 20
    克隆类型
    • 33
    • 16
    单克隆
    标记
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    • 1
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    This MUC6 antibody is un-conjugated
    应用范围
    • 22
    • 20
    • 19
    • 16
    • 15
    • 6
    • 6
    • 6
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    Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    The MUC6 gastric mucin is a secreted glycoprotein that plays an essential role in epithelial cyto-protection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract. Mucin 6 expression is highest in the stomach and gall bladder, with lower expression in the terminal ileum and right colon. In gastric cancer, Mucin 6 has an altered expression. In normal stomach, Mucin 6 is associated with Lewis type 2, Mucin 6 is also expressed in gastric metaplasia, duodenum and pancreas. Mucin 6 is a secretory mucin, located in the deeper mucosal folds of human gall bladder, and its expression is altered with increasing degrees of inflammation.
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant full-length human MUC6 protein
    克隆位点
    MUC6-1553R
    亚型
    IgG
    Top Product
    Discover our top product MUC6 Primary Antibody
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (2-4 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: Human stomach tissue (IHC).

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    MUC6 (Mucin 6, Oligomeric Mucus/gel-Forming (MUC6))
    别名
    MUC6 (MUC6 产品)
    别名
    gastric antibody, MUC-6 antibody, mucin-6-like antibody, mucin 6, oligomeric mucus/gel-forming antibody, mucin 6, gastric antibody, LOC100850574 antibody, MUC6 antibody, Muc6 antibody
    背景
    Gastric mucin 6, MUC6, MUC6 mucin, Mucin 6 oligomeric mucus/gel forming, Mucin glycoprotein Fragment, Mucin-6, Secretory mucin MUC6,MUC6 (Mucin 6 / Gastric Mucin)
    Cellular localisation: Cytoplasmic & Secreted
    分子量
    252kDa
    基因ID
    4588, 528432
    UniProt
    Q6W4X9
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