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MME 抗体 (AA 297-483)

Name: MME 抗体 (AA 297-483)
Brand: antibodies-online
SKU: ABIN6937872
Availability: OutOfStock

MME 适用: 人 IHC, IHC (f) 宿主: 小鼠 Monoclonal MME-1893 unconjugated

产品编号 ABIN6937872

发货至: 中国

Datasheet as PDF

抗原 See all MME 抗体

MME (Membrane Metallo-Endopeptidase (MME))
抗原表位
14

8

8

8

7

7

7

7

6

5

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 297-483
适用
190

44

37

3

2

2

2

2

2

1

1

1

1
人
宿主
99

96

2
小鼠
Compatible Secondaries
克隆类型
105

91

2
单克隆
标记
105

20

16

12

9

5

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This MME antibody is un-conjugated
应用范围
112

79

76

66

34

27

20

18

10

7

5

5

3

3

2

1

1

1

1

1

1
Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

特异性

Recognizes a 100kDa glycoprotein, identified as CD10, also known as Common Acute Lymphocytic Leukemia Antigen (CALLA). It is a cell surface enzyme with neutral metalloendopeptidase activity, which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt's, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML). It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue. CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells.

交叉反应（详细）

Human. Dog

纯化方法

1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

免疫原

Recombinant human CD10 protein fragment (aa297-483) (exact sequence is proprietary)

克隆位点

MME-1893

亚型

IgG2b kappa

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应用备注

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
Positive_Control: Tonsil, small intestine or kidney (IHC).

限制

仅限研究用
浓度

1.0 mg/mL

缓冲液

Prepared in 10 mM PBS, WITHOUT BSA and Azide.

储存液

Azide free

储存条件

-20 °C,-80 °C

储存方法

Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

有效期

24 months
抗原

MME (Membrane Metallo-Endopeptidase (MME))

别名

MME (MME 产品)

别名

CALLA antibody, CD10 antibody, NEP antibody, SFE antibody, 6030454K05Rik antibody, C85356 antibody, Nep antibody, neprilysin antibody, membrane metalloendopeptidase antibody, membrane metallo endopeptidase antibody, membrane metallo-endopeptidase antibody, MME antibody, Mme antibody

物质类

Chemical

背景

Atriopeptidase, Common acute lymphocytic leukemia antigen (CALLA), Enkephalinase (EPN), gp100, Membrane metalloendopeptidase (MME), Neprilysin, Neutral endopeptidase (NEP), Skin fibroblast elastase (SFE),CD10 (Membrane Metalloendopeptidase)
Cellular localisation: Cell Surface and Cytoplasmic

分子量

100kDa

基因ID

4311, 307734

UniProt

P08473

途径

RTK signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration