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Recombinant IgL 抗体

适用: 人 IHC (f) 宿主: 小鼠 Monoclonal rLLC-3777 unconjugated Recombinant Antibody
产品编号 ABIN6937542
发货至: 中国
  • 抗原 See all IgL products
    IgL
    抗体类型
    Recombinant Antibody
    适用
    宿主
    • 9
    • 3
    小鼠
    克隆类型
    • 11
    • 1
    单克隆
    标记
    • 11
    • 1
    This IgL antibody is un-conjugated
    应用范围
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant full-length human IGL protein
    克隆位点
    RLLC-3777
    亚型
    IgG1 kappa
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: 293T, Raji or hPBL cells. Tonsil or Spleen.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    IgL
    Abstract
    IgL 产品
    别名
    IGL@ antibody, IGLC6 antibody, igl antibody, immunoglobulin lambda locus antibody, IGL antibody, igl@ antibody
    背景
    Bence Jones Protein, BJP, IGLC 1/2/3, Mcg Marker, Paraprotein,Lambda Light Chain (B-Cell Marker)
    Cellular localisation: Cell Surface, cytoplasmic and secreted
    分子量
    ~22.5kDa
    基因ID
    3535, 3546, 449585
    UniProt
    P01701, P01842
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