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IGHG 抗体

IGHG 适用: 人 IHC, FACS, IF, IHC (p) 宿主: 小鼠 Monoclonal IG217 unconjugated
产品编号 ABIN6937497
发货至: 中国
  • 抗原 See all IGHG products
    IGHG (Immunoglobulin Heavy Chain (Gamma Polypeptide) (IGHG))
    适用
    • 15
    • 2
    宿主
    • 8
    • 7
    • 2
    小鼠
    克隆类型
    • 15
    • 2
    单克隆
    标记
    • 15
    • 1
    • 1
    This IGHG antibody is un-conjugated
    应用范围
    • 10
    • 10
    • 7
    • 6
    • 6
    • 4
    • 4
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    Recognizes a protein of 75kDa, identified as gamma heavy chain of human immunoglobulins. It reacts with all sub-classes of gamma chain of human immunoglobulins. It does not cross-react with alpha (IgA), mu (IgM), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Purified human Ig Gamma Chain
    克隆位点
    IG217
    亚型
    IgG1 kappa
  • 应用备注

    Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin/paraffin) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: 293T, Raji or hPBL cells. Tonsil or Spleen.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    IGHG (Immunoglobulin Heavy Chain (Gamma Polypeptide) (IGHG))
    别名
    IGHG (IGHG 产品)
    别名
    AU044919 antibody, IGHG2A antibody, Immunoglobulin heavy chain (gamma polypeptide) antibody, Ighg antibody
    背景
    G1m Marker, G2m Marker, G3m Marker, G4m Marker, HDC, Heavy Chain Disease Protein, Human Immunglobulin G, Ig gamma1/2/3/4 Chain C Region, IGHG1, IGHG2, IGHG3, IGHG4, Immunoglobulin Heavy Constant 1/2/3/4,IgG (Immunoglobulin Gamma Heavy Chain) (B-Cell Marker)
    Cellular localisation: Cytoplasm, Cell Surface and Secreted
    分子量
    75kDa
    基因ID
    3500, 3501, 3502
    UniProt
    P01857, P01859, P01860, P01861
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