HLA-DRB3 抗体
-
- 抗原 See all HLA-DRB3 抗体
- HLA-DRB3 (Major Histocompatibility Complex, Class II, DR beta 3 (HLA-DRB3))
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This HLA-DRB3 antibody is un-conjugated
-
应用范围
- Immunofluorescence (IF), Flow Cytometry (FACS)
- 特异性
- This MAb reacts with the HLA-DRB3 antigen, a member of MHC class II molecules.It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kDa alpha (heavy) chain and a 28 kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 Molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts.
- 交叉反应 (详细)
- Human. Baboon. Chimpanzee. Monkey. Squirrel. Dog.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Human REH cells (non-T, non-B leukemia cell line)
- 克隆位点
- Bra30
- 亚型
- IgG2a kappa
- Top Product
- Discover our top product HLA-DRB3 Primary Antibody
-
-
- 应用备注
-
Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: Ramos, Daudi or HuT78 cells. Tonsil or lymph node.
- 限制
- 仅限研究用
-
- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
-
- 抗原
- HLA-DRB3 (Major Histocompatibility Complex, Class II, DR beta 3 (HLA-DRB3))
- 别名
- HLA-DRB3 (HLA-DRB3 产品)
- 别名
- HLA-DR3B antibody, BLA-DRB3 antibody, Bota-DRB01 antibody, Bota-DRB02 antibody, Bota-DRB04 antibody, Bota-DRB07 antibody, Bota-DRB21 antibody, Bota-DRB22 antibody, LA-DRB antibody, major histocompatibility complex, class II, DR beta 3 antibody, major histocompatibility complex, class II, DRB3 antibody, HLA-DRB3 antibody, BOLA-DRB3 antibody
- 背景
-
HLA class II histocompatibility antigen DR beta 3 chain, HLADR3B, Major histocompatibility complex, class II DR beta 3,HLA-DRB (MHC II)
Cellular localisation: Cell Surface - 分子量
- ~28kDa (beta chain)
- 基因ID
- 3123, 534322
- UniProt
- P01911
- 途径
- TCR Signaling, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
-