MHC Class II HLA-DP/DQ/DR 抗体
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- 抗原 See all MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR) products
- MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR)
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This MHC Class II HLA-DP/DQ/DR antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB), Coating (Coat), ELISA, Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DP, -DQ and -DR. Human MHC class II antigens are transmembrane glycoproteins composed of an chain (36 kDa) and a chain (27 kDa). They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six and ten chain genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles.
- 交叉反应 （详细）
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Cells from human tonsil
- 克隆位点
- CR3-43
- 亚型
- IgG1 kappa
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anti-MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR) antibody
HLA-DP/DQ/DR 适用: 人 FACS, IF, IHC, Coat, ELISA, StM 宿主: 小鼠 Monoclonal rHLA-Pan-3475 unconjugated Recombinant Antibody
anti-MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR) antibodyHLA-DP/DQ/DR 适用: 人 FACS, IF, WB, IHC, Coat, ELISA, StM 宿主: 兔 Monoclonal HLA-Pan-2967R unconjugated Recombinant Antibody
anti-MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR) antibodyHLA-DP/DQ/DR 适用: 人 FACS, IF, WB, IHC, Coat, ELISA, StM 宿主: 小鼠 Monoclonal CR3-43 unconjugated
anti-MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR) antibodyGMP Grade HLA-DP/DQ/DR 适用: 人 FACS 宿主: 小鼠 Monoclonal IVA12 unconjugated
anti-MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR) antibodyHLA-DP/DQ/DR 适用: 人 FACS, IHC, IHC (p) 宿主: 小鼠 Monoclonal WR18 unconjugated
anti-MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR) antibody (FITC)GMP Grade HLA-DP/DQ/DR 适用: 人 FACS 宿主: 小鼠 Monoclonal IVA12 FITC
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- 应用备注
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Known_Application: ELISA (For coating use Ab at 2-4 μg/mL, order Ab without BSA),Flow Cytometry (1-2 μg/ million cells), ,Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Ramos, Raji cells. Tonsil, Spleen or lymph node.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- MHC Class II HLA-DP/DQ/DR (HLA-DP/DQ/DR)
- 别名
- HLA-DP, HLA-DQ, HLA-DR (HLA-DP/DQ/DR 产品)
- 背景
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HLA-DPB1, HLA-DQA1, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5,HLA-DP/-DQ/-DR (MHC II)
Cellular localisation: Cell Surface - 分子量
- 36kDa (' chain) and 27kDa (' chain)
- 基因ID
- 3115, 3117, 3122
- UniProt
- P04440, P01908, P01909, P01920, P01903
- 途径
- Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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