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HLA-ABC 抗体

HLA-ABC 适用: 人 FACS, IF 宿主: 小鼠 Monoclonal 246-B8-E7 unconjugated
产品编号 ABIN6937393
发货至: 中国
  • 抗原 See all HLA-ABC 抗体
    HLA-ABC
    适用
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    宿主
    • 61
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    小鼠
    克隆类型
    • 64
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    单克隆
    标记
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    This HLA-ABC antibody is un-conjugated
    应用范围
    • 58
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    Flow Cytometry (FACS), Immunofluorescence (IF)
    特异性
    Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.
    交叉反应 (详细)
    Human. Mouse. Non-Human primates.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Human peripheral blood leukocytes
    克隆位点
    246-B8-E7
    亚型
    IgG2a kappa
    Top Product
    Discover our top product HLA-ABC Primary Antibody
  • 应用备注

    Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

    Positive_Control: THP-1 and Jurkat cells. Tonsil or lymph node.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    HLA-ABC
    别名
    HLA-A, HLA-B, HLA-C (HLA-ABC 产品)
    别名
    HLAA antibody, major histocompatibility complex, class I, A antibody, HLA-A antibody
    背景
    HLA-A, HLA-B, HLA-C, HLA class 1A, HLA class 1B, HLA class 1C, Major histocompatibility complex, class I, A + B + C, MHC class I HLA-A, MHC class I HLA-B, MHC class I HLA-C, MHC HLA-ABC,HLA-ABC (MHC I)
    Cellular localisation: Cell surface
    分子量
    ~41kDa
    基因ID
    3105, 3106, 3107
    UniProt
    P01889, P30443, P30499
    途径
    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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