GPN1 抗体
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- 抗原 See all GPN1 抗体
- GPN1 (GPN-Loop GTPase 1 (GPN1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This GPN1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Coating (Coat)
- 特异性
- GPN1 is involved in protein synthesis events. It is expressed ubiquitously with highest expression in testis. It binds to the RNA polymerase II- (Poll II) associated proteins RPAP1-3 and to XPA (a protein involved in DNA repair mechanisms), thereby forming an interface with Poll II. Via this interaction, GPN1 is thought to mediate the involvement of Pol II in both protein complex formation and protein chaperone/ scaffolding activities. In addition, GPN1 interacts with components of the integrator and molecular chaperone complexes, further implicating GPN1 in protein assembly. GPN1 contains a cluster of acidic amino acids in its C-terminal region and a series of sequences similar to those found in GTP-binding proteins in its N-terminal region, suggesting that GPN1 has possible GTPase activity.
- 交叉反应 (详细)
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant full-length human GPN1 protein
- 克隆位点
- GPN1-2350
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product GPN1 Primary Antibody
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- 应用备注
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Known_Application: ELISA (For coating, order antibody without BSA), Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: Pancreas, Testis, Thyroid or Bladder.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- GPN1 (GPN-Loop GTPase 1 (GPN1))
- 别名
- GPN1 (GPN1 产品)
- 别名
- ATPBD1A antibody, MBDIN antibody, NTPBP antibody, RPAP4 antibody, XAB1 antibody, GPN1 antibody, MGC137872 antibody, 2410004J02Rik antibody, AI449615 antibody, Xab1 antibody, GPN-loop GTPase 1 antibody, GPN1 antibody, Gpn1 antibody
- 背景
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ATP(GTP) binding protein (ATPBD1A), GPN-loop GTPase 1, GPN1, MBD2-interacting protein (MBDin), NTPBP, RNA polymerase II associated protein 4 (RPAP4), XPA-binding protein 1 (XAB1) GTPase,GPN1 / XAB1 (DNA Repair & Protein Synthesis)
Cellular localisation: Cytoplasmic & Nuclear - 分子量
- 42kDa
- 基因ID
- 11321, 18259
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