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CD5 抗体 (AA 269-366)

CD5 适用: 人 FACS, IF, IHC (f) 宿主: 小鼠 Monoclonal CD5-2418 unconjugated
产品编号 ABIN6936752
发货至: 中国
  • 抗原 See all CD5 抗体
    CD5
    抗原表位
    • 16
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    AA 269-366
    适用
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    宿主
    • 168
    • 82
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    小鼠
    克隆类型
    • 225
    • 75
    单克隆
    标记
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    This CD5 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    Recognizes a 67 kDa transmembrane protein, which is identified as CD5. The CD5 antigen is found on 95 % of thymocytes and 72 % of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10 %) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. Anti-CD5 detection is diagnostic in CLL/SLL within a panel of other B-cell markers, especially one that includes anti-CD23. Anti-CD5 is also very useful in differentiating among mature small lymphoid cell malignancies. In addition, anti-CD5 can be used in distinguishing thymic carcinoma (+) from thymoma (-). Anti-CD5 does not react with granulocytes or monocytes.
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant fragment of human CD5 protein (around aa 269-366) (exact sequence is proprietary)
    克隆位点
    CD5-2418
    亚型
    IgG2c kappa
    Top Product
    Discover our top product CD5 Primary Antibody
  • 应用备注

    Known_Application: Flow Cytometry (1-2 μg/million cells),Immunofluorescence (1-2 μg/mg), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: 293T, Ramos or MOLT-4 cells. Tonsil or Lymph Node.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    CD5
    别名
    CD5 (CD5 产品)
    别名
    CD5 antibody, Ly-1 antibody, Ly-12 antibody, Ly-A antibody, Lyt-1 antibody, LEU1 antibody, T1 antibody, CD5 molecule antibody, CD5 antigen antibody, CD5 molecule like antibody, Cd5 molecule antibody, CD5 antibody, Cd5 antibody, CD5L antibody
    背景
    CD5 antigen (p56 62), LEU1, Ly12, LyA, Lymphocyte antigen T1/Leu-1, Lymphocyte glycoprotein T1/Leu1, T-cell surface glycoprotein CD5,CD5 (Mantle Cell Lymphoma Marker)
    Cellular localisation: Cell Surface
    分子量
    67kDa
    基因ID
    921, 58685
    UniProt
    P06127
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