CD14 抗体
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- 抗原 See all CD14 抗体
- CD14
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD14 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunofluorescence (IF)
- 特异性
- Recognizes a protein of 55 kDa, identified as CD14 (also known lipopolysaccharide receptor). CD14 is expressed strongly on monocytes and macrophage and weakly on the surface of neutrophils. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for complexes of LPS and LPS binding protein (LBP). Soluble CD14, also binding to LPS, acts at physiological concentration as an LPS agonist and has, at higher concentrations, an LPS antagonizing effect in cell activation.
- 交叉反应 (详细)
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant human CD14 protein
- 克隆位点
- LPSR-927
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product CD14 Primary Antibody
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- 应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: THP-1 cells and human monocytes. Lymph nodes and tonsils.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- CD14
- 别名
- CD14 (CD14 产品)
- 别名
- CD14 molecule antibody, CD14 antigen antibody, CD14 antibody, Cd14 antibody
- 背景
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Lipopolysaccharide receptor, LPS-R, LPSR, Mo2, Monocyte Differentiation Antigen 14, Myeloid cell-specific leucine-rich glycoprotein,CD14 (Monocyte / Macrophage Marker)
Cellular localisation: Cell Surface - 分子量
- 55kDa
- 基因ID
- 929, 163867
- UniProt
- P08571
- 途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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