IGKC 抗体 (CF®488A)
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- 抗原 See all IGKC products
- IGKC (Immunoglobulin kappa Constant (IGKC))
- 适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This IGKC antibody is conjugated to CF®488A
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应用范围
- Immunohistochemistry (IHC), Staining Methods (StM), Flow Cytometry (FACS)
- 特异性
- This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. It recognizes human Ig kappa light chains of both secreted and cell surface immunoglobulin. It detects also free kappa light chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Recombinant full-length human IGKC protein
- 克隆位点
- KLC709
- 亚型
- IgG1 kappa
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- 应用备注
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Positive Control: 293T, Raji or hPBL cells. Tonsil or Spleen.
Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunohistochemistry (Formalin-fixed) (0.5-1.0 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 100 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Antibody with azide - store at 4 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- IGKC (Immunoglobulin kappa Constant (IGKC))
- 别名
- IGKC (IGKC 产品)
- 别名
- HCAK1 antibody, IGKCD antibody, Km antibody, IGKC antibody, Igk-C antibody, immunoglobulin kappa constant antibody, immunoglobulin kappa constant L homeolog antibody, IGKC antibody, LOC708048 antibody, igkc antibody, igkc.L antibody, Igkc antibody
- 分子量
- ~22.5kDa
- 基因ID
- 3514
- UniProt
- P01601, P01834
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