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- 抗原 See all AMACR 抗体
- AMACR (alpha-Methylacyl-CoA Racemase (AMACR))
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适用
- 人
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This AMACR antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- This antibody recognizes a protein of 54 kDa, which is identified as AMACR, also known as p504S. It is an enzyme that is involved in bile acid biosynthesis and -oxidation of branched-chain fatty acids. AMACR is essential in lipid metabolism. It is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands. AMACR is expressed in normal liver (hepatocytes), kidney (tubular epithelial cells) and gall bladder (epithelial cells). Expression has also been found in lung (bronchial epithelial cells) and colon (colonic surface epithelium). AMACR expression can also be found in hepatocellular carcinoma and kidney carcinoma. Past studies have also shown that AMACR is expressed in various colon carcinomas (well, moderately and poorly differentiated) and over expressed in prostate carcinoma.
- 交叉反应 （详细）
- Human.
- 免疫原
- Full length human recombinant AMACR protein
- 克隆位点
- 13H4
- 亚型
- IgG
- Top Product
- Discover our top product AMACR Primary Antibody
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anti-alpha-Methylacyl-CoA Racemase (AMACR) (AA 297-394) antibody
AMACR 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal AMACR-1864 unconjugated
anti-alpha-Methylacyl-CoA Racemase (AMACR) antibodyAMACR 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal AMACR-1723 unconjugated
anti-alpha-Methylacyl-CoA Racemase (AMACR) (AA 1-198) antibodyAMACR 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-alpha-Methylacyl-CoA Racemase (AMACR) antibodyAMACR 适用: 人 WB, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 2A10F3 unconjugated
anti-alpha-Methylacyl-CoA Racemase (AMACR) (AA 323-351) antibodyAMACR 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-alpha-Methylacyl-CoA Racemase (AMACR) antibodyAMACR 适用: 人 IHC, StM 宿主: 兔 Polyclonal unconjugated
anti-alpha-Methylacyl-CoA Racemase (AMACR) (AA 297-394) antibodyAMACR 适用: 人 IHC, StM 宿主: 兔 Monoclonal AMACR-2748R unconjugated Recombinant Antibody
anti-alpha-Methylacyl-CoA Racemase (AMACR) (AA 297-394) antibodyAMACR 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal rAMACR-1864 unconjugated Recombinant Antibody
anti-alpha-Methylacyl-CoA Racemase (AMACR) (AA 312-326) antibodyVerified AMACR 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-alpha-Methylacyl-CoA Racemase (AMACR) (AA 323-351), (C-Term) antibodyAMACR 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB18736 unconjugated
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- 应用备注
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Known_Application: Western Blot (1:50-1:100), Immunohistochemistry (Formalin-fixed) (1:50-1:100 for 30-60 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 1 mM EDTA, pH 7.5-8.5, for 45 min at 95°C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
Positive_Control: HEK cells. Prostate Adenocarcinoma and human kidney tissue.
- 限制
- 仅限研究用
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- 缓冲液
- Culture Supernatant with 0.05% Azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- AMACR (alpha-Methylacyl-CoA Racemase (AMACR))
- 别名
- AMACR (AMACR 产品)
- 别名
- AMACR antibody, DKFZp469O1232 antibody, amacr antibody, NCU04099.1 antibody, MGC89832 antibody, AMACRD antibody, CBAS4 antibody, RACE antibody, RM antibody, Macr1 antibody, Da1-8 antibody, Marc1 antibody, alpha-methylacyl-CoA racemase antibody, PROBABLE ALPHA-METHYLACYL-COA RACEMASE MCR (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase) antibody, Alpha-methylacyl-CoA racemase antibody, alpha-methylacyl-CoA racemase L homeolog antibody, AMACR antibody, mcr antibody, BPSL0064 antibody, Maqu_2037 antibody, UREG_03852 antibody, MCYG_01809 antibody, amacr antibody, amacr.L antibody, MGYG_04259 antibody, NCU04099 antibody, Amacr antibody
- 背景
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Alpha-methylacyl-CoA Racemase, CBAS4, Da1-8, Macr1, RACE, RM,AMACR / p504S (Prostate Cancer Marker)
Cellular localisation: Cytoplasmic - 分子量
- 42kDa
- 基因ID
- 23600, 508343
- UniProt
- Q9UHK6
- 途径
- Monocarboxylic Acid Catabolic Process
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