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CD63 抗体 (AA 101-200)

Name: CD63 抗体 (AA 101-200)
SKU: ABIN687742
Availability: OutOfStock

CD63 适用: 人, 小鼠 FACS, WB, ELISA, IHC (p), ICC, IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated

(A) Western Blot analysis of proteins present (Hsp90, CD63 and TSG101) or absent (calnexin) in exosomes and abundant in bovine milk (β-casein). (CD63 抗体 (AA 101-200))

Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-CD63/MLA1 Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining. (CD63 抗体 (AA 101-200))

IHC (p)

HepG2 cells probed with CD63/MLA1 Polyclonal Antibody, Unconjugated at 1:100 for 30 minutes followed by incubation with a conjugated secondary (PE Conjugated) (green) for 30 minutes compared to control cells (blue), secondary only (light blue) and isotype control (orange). (CD63 抗体 (AA 101-200))

FACS

3 images

(4 references)

产品编号 ABIN687742

发货至: 中国

Datasheet as PDF

抗原 See all CD63 抗体

CD63
抗原表位
13

9

6

4

4

2

1

1

1

1

1

1

1
AA 101-200
适用
125

48

11

3

2

1
人, 小鼠
宿主
75

61

4

2

1

1
兔
Compatible Secondaries
克隆类型
97

44

3
多克隆
标记
71

12

11

7

7

4

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1
This CD63 antibody is un-conjugated
应用范围
89

62

48

42

33

28

26

19

18

11

5

3

2

2

1

1

1

1

1
Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

交叉反应

人, 小鼠

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human CD63

亚型

IgG

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anti-CD63 (CD63) (AA 120-175) antibody
CD63 适用: 人, 小鼠, 大鼠, 猴, 犬 FACS, WB, IHC, IF 宿主: 山羊 Polyclonal unconjugated

anti-CD63 (CD63) antibody
CD63 适用: 人 FACS, IHC (p), IP, ICC 宿主: 小鼠 Monoclonal MEM-259 unconjugated

anti-CD63 (CD63) antibody (Biotin)
CD63 适用: 人 FACS, IHC (p), IP, ICC 宿主: 小鼠 Monoclonal MEM-259 Biotin

anti-CD63 (CD63) antibody (APC)
CD63 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-259 APC

anti-CD63 (CD63) (AA 103-203) antibody
CD63 适用: 人 FACS, WB, IHC, IF, ELISA 宿主: 小鼠 Monoclonal 10F11E6 unconjugated

anti-CD63 (CD63) (AA 103-203) antibody
CD63 适用: 人 FACS, WB, IHC, IF, ELISA 宿主: 小鼠 Monoclonal 1H1E11 unconjugated

anti-CD63 (CD63) antibody
CD63 适用: 人, 小鼠 FACS, WB, IHC, IF, ISt, StM 宿主: 小鼠 Monoclonal MX-49-129-5 unconjugated

anti-CD63 (CD63) antibody (PerCP)
CD63 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-259 PerCP

anti-CD63 (CD63) antibody (PE)
CD63 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-259 PE

anti-CD63 (CD63) (AA 103-203) antibody
CD63 适用: 人 FACS, IHC, ELISA 宿主: 小鼠 Monoclonal 1E8D4 unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Del Pozo-Acebo, Hazas, Tomé-Carneiro, Gil-Cabrerizo, San-Cristobal, Busto, García-Ruiz, Dávalos: "Bovine Milk-Derived Exosomes as a Drug Delivery Vehicle for miRNA-Based Therapy." in: International journal of molecular sciences, Vol. 22, Issue 3, (2021) (PubMed).

Marzesco, Flötenmeyer, Bühler, Obermüller, Staufenbiel, Jucker, Baumann: "Highly potent intracellular membrane-associated Aβ seeds." in: Scientific reports, Vol. 6, pp. 28125, (2016) (PubMed).

Sun, Zhao, Li, Wang, Nie, Peng, Wang, Zhang, Tian, Li, Song, Wang, Xu, Tian, Zhao, Xu, Zhong, Han, Ling, Chang, Li: "Osteoclast-derived microRNA-containing exosomes selectively inhibit osteoblast activity." in: Cell discovery, Vol. 2, pp. 16015, (2016) (PubMed).

Son, Rahimian, Shin, Siltanen, Patel, Revzin: "Microfluidic compartments with sensing microbeads for dynamic monitoring of cytokine and exosome release from single cells." in: The Analyst, (2015) (PubMed).
抗原

CD63

别名

CD63/MLA1 (CD63 产品)

背景

Synonyms: MLA1, ME491, LAMP-3, OMA81H, TSPAN3, CD63 antigen, Granulophysin, Lysosomal-associated membrane protein 3, Melanoma-associated antigen ME491, Ocular melanoma-associated antigen, Tetraspanin-3, Tspan-3, CD63
Background: Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli.

基因ID

967

UniProt

P08962