BIRC6 抗体 (AA 4701-4857)
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- 抗原 See all BIRC6 抗体
- BIRC6 (Baculoviral IAP Repeat-Containing 6 (BIRC6))
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抗原表位
- AA 4701-4857
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BIRC6 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人
- 预测反应
- Mouse,Rat,Cow,Pig,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Apollon
- 亚型
- IgG
- Top Product
- Discover our top product BIRC6 Primary Antibody
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- 应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- BIRC6 (Baculoviral IAP Repeat-Containing 6 (BIRC6))
- 别名
- Apollon/BIRC6 (BIRC6 产品)
- 别名
- APOLLON antibody, BRUCE antibody, bruce antibody, apollon antibody, BIRC6 antibody, A430032G04Rik antibody, A430040A19Rik antibody, AA501170 antibody, Bruce antibody, D630005A10Rik antibody, mKIAA1289 antibody, baculoviral IAP repeat containing 6 antibody, baculoviral IAP repeat-containing 6 antibody, BIRC6 antibody, Birc6 antibody, birc6 antibody
- 背景
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Synonyms: BRUCE, APOLLON, Baculoviral IAP repeat-containing protein 6, BIR repeat-containing ubiquitin-conjugating enzyme, Ubiquitin-conjugating BIR domain enzyme apollon, BIRC6, KIAA1289
Background: Anti-apoptotic protein which can regulate cell death by controlling caspases and by acting as an E3 ubiquitin-protein ligase. Has an unusual ubiquitin conjugation system in that it could combine in a single polypeptide, ubiquitin conjugating (E2) with ubiquitin ligase (E3) activity, forming a chimeric E2/E3 ubiquitin ligase. Its tragets include CASP9 and DIABLO/SMAC. Acts as an inhibitor of CASP3, CASP7 and CASP9. Important regulator for the final stages of cytokinesis. Crucial for normal vesicle targeting to the site of abscission, but also for the integrity of the midbody and the midbody ring, and its striking ubiquitin modification.
- 基因ID
- 57448
- UniProt
- Q9NR09
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