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- 抗原 See all TRAP1 抗体
- TRAP1 (TNF Receptor-Associated Protein 1 (TRAP1))
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抗原表位
- AA 501-650
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TRAP1 antibody is conjugated to FITC
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应用范围
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 大鼠
- 预测反应
- Human,Mouse,Horse,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human HSP75
- 亚型
- IgG
- Top Product
- Discover our top product TRAP1 Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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TRAP1 regulates stemness through Wnt/β-catenin pathway in human colorectal carcinoma." in: Cell death and differentiation, Vol. 23, Issue 11, pp. 1792-1803, (2016) (PubMed).
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TRAP1 regulates stemness through Wnt/β-catenin pathway in human colorectal carcinoma." in: Cell death and differentiation, Vol. 23, Issue 11, pp. 1792-1803, (2016) (PubMed).
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- 抗原
- TRAP1 (TNF Receptor-Associated Protein 1 (TRAP1))
- 别名
- Hsp75/Trap1 (TRAP1 产品)
- 别名
- HSP 75 antibody, HSP75 antibody, HSP90L antibody, TRAP-1 antibody, 2410002K23Rik antibody, fc85a11 antibody, wu:fc85a11 antibody, TNF receptor associated protein 1 antibody, TNF receptor-associated protein 1 antibody, TRAP1 antibody, Trap1 antibody, trap1 antibody
- 背景
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Synonyms: HSP75, HSP 75, HSP90L, TRAP-1, Heat shock protein 75 kDa, mitochondrial, TNFR-associated protein 1, Tumor necrosis factor type 1 receptor-associated protein, TRAP1
Background: Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, most likely through stabilization of mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.
- 基因ID
- 10131
- UniProt
- Q12931
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