MTA1 抗体 (AA 601-715)
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- 抗原 See all MTA1 抗体
- MTA1 (Metastasis Associated 1 (MTA1))
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抗原表位
- AA 601-715
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MTA1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human MTA1
- 亚型
- IgG
- Top Product
- Discover our top product MTA1 Primary Antibody
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anti-Metastasis Associated 1 (MTA1) (AA 601-700) antibody
MTA1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4D5 unconjugated
anti-Metastasis Associated 1 (MTA1) (AA 601-700) antibodyMTA1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4D11 unconjugated
anti-Metastasis Associated 1 (MTA1) (AA 601-700) antibodyMTA1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1C3 unconjugated
anti-Metastasis Associated 1 (MTA1) (AA 541-715) antibodyMTA1 适用: 人 WB, ELISA, IHC, ICC, FACS, Neut 宿主: 小鼠 Monoclonal 6B1E9 unconjugated
anti-Metastasis Associated 1 (MTA1) antibodyMTA1 适用: 人 IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Metastasis Associated 1 (MTA1) (AA 541-715) antibodyMTA1 适用: 人 WB, ELISA, IHC, ICC, FACS, Neut 宿主: 小鼠 Monoclonal 7G9C10 unconjugated
anti-Metastasis Associated 1 (MTA1) (Internal Region) antibodyMTA1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Metastasis Associated 1 (MTA1) (Internal Region) antibodyVerified MTA1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Metastasis Associated 1 (MTA1) (AA 659-687), (C-Term) antibodyMTA1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal RB40949 unconjugated
anti-Metastasis Associated 1 (MTA1) (AA 1-255) antibodyMTA1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- MTA1 (Metastasis Associated 1 (MTA1))
- 别名
- MTA1 (MTA1 产品)
- 别名
- Tex22 antibody, metastasis associated 1 antibody, metastasis associated 1 L homeolog antibody, MTA1 antibody, Mta1 antibody, mta1.L antibody
- 背景
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Synonyms: Metastasis-associated protein MTA1, MTA1
Background: Transcriptional coregulator which can act as both a transcriptional corepressor and coactivator. As a part of the histone-deacetylase multiprotein complex (NuRD), regulates transcription of its targets by modifying the acetylation status of the target chromatin and cofactor accessibility to the target DNA. In conjunction with other components of NuRD, acts as a transcriptional corepressor of BRCA1, ESR1, TFF1 and CDKN1A. Acts as a transcriptional coactivator of BCAS3, PAX5 and SUMO2, independent of the NuRD complex. Stimulates the expression of WNT1 by inhibiting the expression of its transcriptional corepressor SIX3. Plays a role in the inflammatory responses, both as a target and as a component of the NF-kappa-B signaling and regulates a subset of proinflammatory cytokines such as IL1B, MIP2, and TNF. Regulates p53-dependent and -independent DNA repair processes following genotoxic stress. Regulates the stability and function of p53/TP53 by inhibiting its ubiquitination by COP1 and MDM2 thereby regulating the p53-dependent DNA repair. Plays an important role in tumorigenesis, tumor invasion, and metastasis. Involved in the epigenetic regulation of ESR1 expression in breast cancer in a TFAP2C, IFI16 and HDAC4/5/6-dependent manner. Plays a role in the regulation of the circadian clock and is essential for the generation and maintenance of circadian rhythms under constant light and for normal entrainment of behavior to light-dark (LD) cycles. Positively regulates the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of its own transcription and the transcription of CRY1. Regulates deacetylation of ARNTL/BMAL1 by regulating SIRT1 expression, resulting in derepressing CRY1-mediated transcription repression. Isoform Short binds to ESR1 and sequesters it in the cytoplasm and enhances its non-genomic responses.
- 基因ID
- 9112
- UniProt
- Q13330
- 途径
- Chromatin Binding
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